公开(公告)号：US08260488B2

公开(公告)日：2012-09-04

申请号：US12543902

申请日：2009-08-19

申请人： Tomoyasu Ishikawa ,  Toshiyuki Abe

发明人： Tomoyasu Ishikawa ,  Toshiyuki Abe

IPC分类号： G01M17/00 ,  G06F7/00 ,  G06F19/00

CPC分类号： G07C5/085 ,  G07C5/008

摘要： When an abnormality of a vehicle is detected based on a vehicle state value that indicates the vehicle state, an abnormality analysis system for the vehicle estimates a cause of the abnormality. The abnormality analysis system includes: a factor identifying information extraction unit that extracts factor identifying information which is used to identify a factor of the abnormality based on the vehicle state value; a database that contains data groups which correspond to respective categories of the factor identifying information and which store causes of abnormalities and vehicle state values at the time of occurrence of the abnormalities; and an abnormality cause estimation unit that executes a process for estimating the cause of the abnormality of the vehicle with the use of the data group that corresponds to the category of the factor identifying information extracted by the factor identifying information extraction unit.

摘要翻译： 当基于指示车辆状态的车辆状态值检测到车辆的异常时，车辆的异常分析系统估计异常的原因。 异常分析系统包括：因子识别信息提取单元，其根据车辆状态值提取用于识别异常因子的因子识别信息; 数据库，其包含对应于因子识别信息的各个类别的数据组，并且在异常发生时存储异常原因和车辆状态值; 以及异常原因估计单元，其使用与由因子识别信息提取单元提取的因子识别信息的类别对应的数据组来执行用于估计车辆的异常原因的处理。

公开(公告)号：US08791803B2

公开(公告)日：2014-07-29

申请号：US13112248

申请日：2011-05-20

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： B60Q1/00

CPC分类号： G01M15/042 ,  G07C5/0816

摘要： An abnormality detection apparatus has: an abnormality detection portion that detects at least one of an abnormality of a vehicle and an abnormality of an in-vehicle device based on an output of the in-vehicle device that indicates a state of a vehicle; an environmental drive condition information obtaining portion that obtains information regarding an environmental drive condition that affects the output of the in-vehicle device; and an abnormality detection criteria changing portion that changes an abnormality detection criteria used by the abnormality detecting portion based on the environmental drive condition information obtained by the environmental drive condition information obtaining portion.

摘要翻译： 异常检测装置具有：异常检测部，其基于表示车辆的状态的车载装置的输出，检测车辆的异常和车内装置的异常中的至少一个; 获取关于影响车载装置的输出的环境驱动条件的信息的环境驱动条件信息获取部; 以及异常检测基准变更部，其根据由环境驱动条件信息获取部获得的环境驱动条件信息，改变异常检测部所使用的异常检测标准。

公开(公告)号：US20100250061A1

公开(公告)日：2010-09-30

申请号：US12741999

申请日：2009-01-15

申请人： Naoki Toyofuku ,  Tomoyasu Ishikawa

发明人： Naoki Toyofuku ,  Tomoyasu Ishikawa

IPC分类号： G06F7/00

CPC分类号： G07C5/085

摘要： A vehicle control device includes a control unit controlling an in-vehicle device and a status information acquisition unit acquiring status information of a vehicle and output the acquired status information to the control unit. In the vehicle control device, the control unit specifies a failure-cause-verification information to be used for verifying a cause of a failure from among the status information acquired by the status information acquisition unit, the failure-cause-verification information being specified by using a timing when a predetermined fail-safe control is started as a reference, the timing being determined based on the status information acquired by the status information acquisition unit, and the control unit stores the specified failure-cause-verification information in a predetermined storage medium.

摘要翻译： 车辆控制装置包括控制车内装置的控制单元和获取车辆的状态信息的状态信息获取单元，并将所获取的状态信息输出到控制单元。 在车辆控制装置中，控制单元从由状态信息获取单元获取的状态信息中指定用于验证故障原因的故障原因验证信息，故障原因验证信息由 当以预定的故障安全控制开始作为参考的定时时，基于由状态信息获取单元获取的状态信息来确定定时，并且控制单元将指定的故障原因验证信息存储在预定存储器 中。

公开(公告)号：US20090163563A1

公开(公告)日：2009-06-25

申请号：US12325706

申请日：2008-12-01

申请人： Thomas M. Razler ,  Amos B. Smith, III ,  Jeffrey P. Ciavarri ,  Tomoyasu Hirose ,  Tomoyasu Ishikawa

发明人： Thomas M. Razler ,  Amos B. Smith, III ,  Jeffrey P. Ciavarri ,  Tomoyasu Hirose ,  Tomoyasu Ishikawa

IPC分类号： A61K31/424 ,  C07D498/22 ,  C12N5/02

CPC分类号： C07D498/22

摘要： Novel macrolactone compounds, their methods of preparation, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the macrolactone compounds may be useful, inter alia, for treating various cancers, inducing apoptosis in malignant cells, or inhibiting cancer cell division.

摘要翻译： 公开了新型的大分子内酯，其制备方法，含有这些化合物的药物组合物及其制药方法。 在某些实施方案中，大分子内酯化合物尤其可用于治疗各种癌症，诱导恶性细胞凋亡或抑制癌细胞分裂。

公开(公告)号：US07889072B2

公开(公告)日：2011-02-15

申请号：US12208681

申请日：2008-09-11

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G08B1/08 ,  B60Q1/00 ,  G06F19/00 ,  G06F11/30 ,  G01M17/00 ,  G01R31/00

CPC分类号： G01S7/529 ,  G01S7/52004

摘要： A failure information detection device that detects abnormality of a vehicle-mounted device that is mounted in a vehicle has: an attachment detection portion that detects whether a first component part has been attached to the vehicle; an abnormality detection portion that detects abnormality of a second component part that is disposed on the first component part; and an abnormality information discernment portion that discerns that abnormality information regarding the abnormality is not based on a failure of the vehicle-mounted device if the attachment detection portion detects that the first component part has not been attached to the vehicle.

摘要翻译： 一种检测安装在车辆中的车载装置的异常的故障信息检测装置具有：检测第一部件是否已经安装在车辆上的附件检测部; 异常检测部，其检测配置在所述第一部件上的第二部件的异常; 以及异常信息识别部，其在所述附着检测部检测到所述第一部件未附接到所述车辆的情况下，识别出所述异常的异常信息不是基于所述车载装置的故障。

公开(公告)号：US07507740B2

公开(公告)日：2009-03-24

申请号：US10592812

申请日：2005-06-01

申请人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Masaki Seto

发明人： Tomoyasu Ishikawa ,  Hiroshi Banno ,  Masaki Seto

IPC分类号： C07D487/04 ,  A61K31/519 ,  A61P35/04

CPC分类号： C07D487/04 ,  C07D487/16

摘要： The present invention relates to a compound represented by the formula: wherein W is C(R1) or N, each A is an optionally substituted aryl group or a heteroaryl group, X1 is —NR3—Y1—, —O—, —S—, —SO—, —SO2— or —CHR3— wherein R3 is a hydrogen atom or an optionally substituted aliphatic hydrocarbon group, or R3 is optionally bonded to A to form an optionally substituted ring structure, R1 is a hydrogen atom or an optionally substituted group bonded via a carbon atom, a nitrogen atom or an oxygen atom, R2 is a hydrogen atom or optionally substituted group bonded via a carbon atom or a sulfur atom, or R1 and R2, or R2 and R3 are optionally bonded to form an optionally substituted ring structure, or a salt thereof, and a tyrosine kinase inhibitor or an agent for the prophylaxis or treatment of cancer, which contains this compound or a prodrug thereof.

摘要翻译： 本发明涉及由下式表示的化合物：其中W是C（R 1）或N，每个A是任选取代的芳基或杂芳基，X 1是-NR 3 -Y 1 - ， - O - ， - ，-SO-，-SO 2 - 或-CHR 3 - ，其中R 3是氢原子或任选取代的脂族烃基，或R 3任选地键合到A上以形成任选取代的环结构，R 1是氢原子或任选被取代的 通过碳原子，氮原子或氧原子键合的基团，R 2是氢原子或经由碳原子或硫原子键合的任选取代的基团，或R 1和R 2，或R 2和R 3可任选地键合形成任选地 取代的环结构或其盐，以及含有该化合物或其前药的酪氨酸激酶抑制剂或用于预防或治疗癌症的药剂。

公开(公告)号：US09721399B2

公开(公告)日：2017-08-01

申请号：US12368885

申请日：2009-02-10

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G07C5/08 ,  G07C5/00

CPC分类号： G07C5/0808 ,  G07C5/008

摘要： A vehicle diagnosing apparatus, a vehicle diagnosing system, and a diagnosing method enable the determination of completion of a repair or part replacement on a vehicle while adapting to changes in environment and overcoming temporal or spatial restrictions. The vehicle diagnosing apparatus reads diagnostic information from an on-board diagnosing unit on the vehicle that detects an abnormality in an on-board device. A result of a maintenance work performed on the on-board device is finalized by a maintenance result finalizing unit. A determination unit determines the appropriateness of the finalized maintenance work result with reference to determination information stored in a database that is continuously updated. The result of the determination is indicated by a notifying unit. Analogy is used to obtain the diagnostic information when the on-board device requires a long time or a certain condition to provide accurate diagnostic information.

公开(公告)号：US20070021479A1

公开(公告)日：2007-01-25

申请号：US11408573

申请日：2006-04-20

申请人： Thomas Razler ,  Amos Smith ,  Jeffrey Ciavarri ,  Tomoyasu Hirose ,  Tomoyasu Ishikawa

发明人： Thomas Razler ,  Amos Smith ,  Jeffrey Ciavarri ,  Tomoyasu Hirose ,  Tomoyasu Ishikawa

IPC分类号： A61K31/424 ,  C07D491/22

CPC分类号： C07D498/22

摘要： Novel macrolactone compounds, their methods of preparation, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the macrolactone compounds may be useful, inter alia, for treating various cancers, inducing apoptosis in malignant cells, or inhibiting cancer cell division.

摘要翻译： 公开了新型的大分子内酯，其制备方法，含有这些化合物的药物组合物及其制药方法。 在某些实施方案中，大分子内酯化合物尤其可用于治疗各种癌症，诱导恶性细胞凋亡或抑制癌细胞分裂。

公开(公告)号：US06906055B2

公开(公告)日：2005-06-14

申请号：US10343285

申请日：2001-08-10

申请人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

发明人： Tomoyasu Ishikawa ,  Shohei Hashiguchi ,  Yuji Iizawa

IPC分类号： A61K31/675 ,  A61P31/04 ,  C07D501/14 ,  C07F9/6561 ,  C07D501/59 ,  A61K31/546

CPC分类号： A61K31/675 ,  C07F9/65613

摘要： A cephem compound (particularly its crystal) represented by the formula [I], wherein X is CH3COOH, CH3CH2COOH or CH3CN, and n is 0 to 5, is useful as an antibacterial agent (particularly anti-MRSA agent) and shows superior quality such as high solid stability, possible long-term stable preservation and the like.

摘要翻译： 由式[I]表示的头孢烯化合物（特别是其结晶），其中X是CH 3 COOH，CH 3 CH 2 COOH或 CH 3 CN，n为0〜5，可用作抗菌剂（特别是抗MRSA剂），并且具有优异的质量，例如高固体稳定性，可能的长期稳定保存等 。

公开(公告)号：US20110029186A1

公开(公告)日：2011-02-03

申请号：US12935997

申请日：2009-04-02

申请人： Tomoyasu Ishikawa

发明人： Tomoyasu Ishikawa

IPC分类号： G06F7/00

CPC分类号： G07C5/0808

摘要： A failure diagnostic information generating apparatus includes a repair information acquiring unit that acquires repair information indicating the content of repair or replacement conducted for a vehicle malfunction or a cause of the malfunction; an malfunction-time vehicle information acquiring unit that acquires malfunction-time vehicle information indicating a vehicle state detected when the malfunction occurs; an instruction information generating unit that generates instruction information, usable for future repair or replacement, on the basis of the repair information and the malfunction-time vehicle information; and a recurrence information acquiring unit that acquires recurrence information indicating whether the malfunction has recurred after the repair or replacement. It is determined, using the recurrence information, whether the malfunction has recurred after the repair or replacement. On the basis of the determination result, the instruction information generating unit determines whether to generate instruction information or whether to use generated instruction information for future repair or replacement.

摘要翻译： 故障诊断信息生成装置包括维修信息取得部，其获取表示对于车辆故障进行的维修或更换的内容的修理信息或故障的原因; 故障时车辆信息获取单元，其获取指示在发生故障时检测到的车辆状态的故障时车辆信息; 指令信息生成单元，其基于修理信息和故障时间车辆信息生成可用于将来的维修或更换的指示信息; 以及重发信息获取单元，其获取指示在所述修复或更换之后所述故障是否复发的复发信息。 使用复发信息确定维修或更换后故障是否复发。 根据判定结果，指示信息生成部判断是否生成指示信息，或者是否使用生成的指示信息来进行将来的修理或替换。