公开(公告)号：US06660504B2

公开(公告)日：2003-12-09

申请号：US10042280

申请日：2002-01-11

申请人： Tsuneo Yamane ,  Yugo Iwasaki ,  Yukiko Mizumoto ,  Masaaki Kasai ,  Takahiro Okada

发明人： Tsuneo Yamane ,  Yugo Iwasaki ,  Yukiko Mizumoto ,  Masaaki Kasai ,  Takahiro Okada

IPC分类号： C12N916

CPC分类号： C12P7/6481 ,  C12P13/00 ,  C12P13/06

摘要： The present invention provides a process for preparing a phospholipid in an aqueous system in which hydrolysis is extremely controlled, and the synthetic yield is improved. A process for exchanging a base of a phospholipid as a raw material by subjecting the phospholipid to the action of phospholipase D in the presence of a receptor having a hydroxyl group, in which the reaction is carried out in an aqueous system, a phospholipid adsorbed on a carrier is used as a raw material phospholipid, and the receptor and the phospholipase D are used in free forms.

摘要翻译： 本发明提供了一种在水性体系中制备磷脂的方法，其中水解被极度控制，并且合成产率提高。1.一种通过使磷脂作用磷脂酶作为原料来交换磷脂的碱的方法 在具有羟基的受体的存在下，其中反应在水性体系中进行，吸附在载体上的磷脂用作原料磷脂，受体和磷脂酶D以游离形式使用 。