公开(公告)号：US20050266568A1

公开(公告)日：2005-12-01

申请号：US11101658

申请日：2005-04-08

申请人： Tsuyoshi Fujihara ,  Shozo Fujita ,  Shunsaku Takeishi ,  Kenji Arinaga ,  Yoshitaka Yamaguchi ,  Tatsuya Usuki ,  Ulrich Rant ,  Karin Buchholz ,  Marc Tornow

发明人： Tsuyoshi Fujihara ,  Shozo Fujita ,  Shunsaku Takeishi ,  Kenji Arinaga ,  Yoshitaka Yamaguchi ,  Tatsuya Usuki ,  Ulrich Rant ,  Karin Buchholz ,  Marc Tornow

IPC分类号： A61K48/00 ,  A61N1/30 ,  C12M1/00 ,  C12N5/10 ,  C12N15/87 ,  C12Q1/68

CPC分类号： A61K48/0083

摘要： A molecule-releasing apparatus includes a releasing unit configured to release molecules, wherein the releasing unit comprises at least one conductive member and releases molecules electrically interacting with the conductive member to which a potential is applied, from the conductive member by changing the potential so as to remove the interaction. In a moleculue-releasing method, molecules electrically attracted to two or more conductive members are released by electrical repulsion from the conductive members at different times. The molecule-releasing apparatus and molecule-releasing method are capable of efficiently releasing or transferring various useful molecules such as DNA molecules, into targets such as cells and can be safely applied for use in gene therapy and other applications.

摘要翻译： 分子释放装置包括配置成释放分子的释放单元，其中释放单元包括至少一个导电构件，并且通过改变电位从导电构件释放与施加电位的导电构件电相互作用的分子，从而 去除互动。 在分子释放方法中，电吸引到两个或更多导电构件的分子在不同时间通过电导电从导电构件释放。 分子释放装置和分子释放方法能够有效地将诸如DNA分子的各种有用分子释放或转移到诸如细胞的靶中，并且可以安全地应用于基因治疗和其它应用中。

公开(公告)号：US06870235B2

公开(公告)日：2005-03-22

申请号：US10436372

申请日：2003-05-13

申请人： Gerhard Abstreiter ,  Marc Uwe Tornow ,  Karin Buchholz ,  Sebastian Markus Luber ,  Erich Sackmann ,  Andreas Richard Bausch ,  Michael Gerold Hellmut Nikolaides ,  Stefan Rauschenbach

发明人： Gerhard Abstreiter ,  Marc Uwe Tornow ,  Karin Buchholz ,  Sebastian Markus Luber ,  Erich Sackmann ,  Andreas Richard Bausch ,  Michael Gerold Hellmut Nikolaides ,  Stefan Rauschenbach

IPC分类号： G01N27/414 ,  H01L29/786

CPC分类号： G01N27/4145

摘要： A Semiconductor sensor device for the detection of target molecules and molecular interactions, based on Silicon-on-Insulator (SOI) technology.

摘要翻译： 用于基于绝缘体上硅（SOI）技术检测靶分子和分子相互作用的半导体传感器装置。