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    Integrated cold plasma and high frequency plasma electrosurgical system and method
    1.
    发明授权
    Integrated cold plasma and high frequency plasma electrosurgical system and method 有权

    公开(公告)号：US10973564B2

    公开(公告)日：2021-04-13

    申请号：US15991609

    申请日：2018-05-29

    申请人： U.S. Patent Innovations LLC

    发明人： Jerome Canady ,  Alexey Shashurin ,  Michael Keidar ,  Taisen Zhuang

    IPC分类号： A61B18/12 ,  A61B18/04 ,  A61B18/14 ,  H05H1/46 ,  A61B18/00

    摘要： An integrated gas-enhanced electrosurgical generator. The generator comprises a high frequency power module, a low frequency power module and a gas module. The high frequency power module adapted to generate an electrical energy having a band of frequencies centered around a first frequency, wherein the electrical energy has a first power as the first frequency and a second power lower than the first power at a second frequency lower than the first frequency. The low frequency power module having an input connected to an output of the high frequency module. The low frequency module comprises a resonant transformer comprising a ferrite core, a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, wherein the resonant transformer has a resonant frequency equal to the second frequency. The gas module is adapted to control a flow of an inert gas.

    INTEGRATED COLD PLASMA AND HIGH FREQUENCY PLASMA ELECTROSURGICAL SYSTEM AND METHOD
    4.
    发明申请
    INTEGRATED COLD PLASMA AND HIGH FREQUENCY PLASMA ELECTROSURGICAL SYSTEM AND METHOD 有权

    公开(公告)号：US20210030459A1

    公开(公告)日：2021-02-04

    申请号：US17076451

    申请日：2020-10-21

    申请人： U.S. Patent Innovations LLC

    发明人： Jerome Canady ,  Alexey Shashurin ,  Michael Keidar ,  Taisen Zhuang

    IPC分类号： A61B18/04 ,  H05H1/46 ,  A61B18/12

    摘要： An integrated gas-enhanced electrosurgical generator. The generator comprises a high frequency power module, a low frequency power module and a gas module. The high frequency power module adapted to generate an electrical energy having a band of frequencies centered around a first frequency, wherein the electrical energy has a first power as the first frequency and a second power lower than the first power at a second frequency lower than the first frequency. The low frequency power module having an input connected to an output of the high frequency module. The low frequency module comprises a resonant transformer comprising a ferrite core, a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, wherein the resonant transformer has a resonant frequency equal to the second frequency. The gas module is adapted to control a flow of an inert gas.

    System and method for selective ablation of cancer cells with cold atmospheric plasma
    5.
    发明授权
    System and method for selective ablation of cancer cells with cold atmospheric plasma 有权

    公开(公告)号：US10023858B2

    公开(公告)日：2018-07-17

    申请号：US14934129

    申请日：2015-11-05

    申请人： U.S. Patent Innovations, LLC

    发明人： Jerome Canady ,  Alexey Shashurin ,  Michael Keidar ,  Taisen Zhuang ,  Arpitha Parthasarathy

    IPC分类号： A61B18/12 ,  C12N13/00 ,  A61B18/04 ,  A61B18/14 ,  H05H1/46 ,  A61B18/00

    摘要： A method for elevating a TRAIL-R1 expression in cancer cells to induce apoptosis. The method comprises the steps of receiving electrical energy having a specific voltage, frequency and power from an electrosurgical generator, up-converting the voltage and down-converting the frequency with a high voltage transformer having a primary coil and a secondary coil, the secondary coil having a larger number of turns than the primary coil, applying said converted electrical energy to an electrode in an electrosurgical hand piece, flowing an inert gas through said electrosurgical hand piece to produce a cold plasma at a distal end of said electrosurgical hand piece; and applying said cold plasma to cancer cells for 1 to 3 minutes. The inert gas may comprise, for example, helium or argon. In a preferred embodiment the cold plasma is applied to cancer cells for about 2 minutes.