公开(公告)号：US20240335224A1

公开(公告)日：2024-10-10

申请号：US18747645

申请日：2024-06-19

申请人： INSIGHTFUL INSTRUMENTS, INC.

发明人： Michael W. WILTBERGER ,  Phillip GOODING ,  Dan E. ANDERSEN

IPC分类号： A61B18/04 ,  A61B18/00 ,  A61B18/14 ,  A61F9/007 ,  H05H1/46

CPC分类号： A61B18/042 ,  A61B2018/0019 ,  A61B2018/00601 ,  A61B2018/144 ,  A61F9/00781 ,  A61F9/0079 ,  H05H1/466 ,  H05H2245/32

摘要： An elongate electrode is configured to flex and generate plasma to incise tissue. An electrical energy source operatively coupled to the electrode is configured to provide electrical energy to the electrode to generate the plasma. A tensioning element is operatively coupled to the elongate electrode. The tensioning element can be configured to provide tension to the elongate electrode to allow the elongate electrode to flex in response to the elongate electrode engaging the tissue and generating the plasma. The tensioning element operatively coupled to the flexible elongate electrode may allow for the use of a small diameter electrode, such as a 5 μm to 20 μm diameter electrode, which can allow narrow incisions to be formed with decreased tissue damage. In some embodiments, the tensioning of the electrode allows the electrode to more accurately incise tissue by decreasing variations in the position of the electrode along the incision path.

公开(公告)号：US12102380B2

公开(公告)日：2024-10-01

申请号：US17021798

申请日：2020-09-15

申请人： Fractyl Health, Inc.

发明人： Harith Rajagopalan ,  Jay Caplan ,  R. Maxwell Flaherty ,  J. Christopher Flaherty

IPC分类号： A61B18/18 ,  A61B18/14 ,  A61B17/32 ,  A61B18/00 ,  A61B18/02 ,  A61B18/04 ,  A61B18/20 ,  A61B18/22

CPC分类号： A61B18/1492 ,  A61B2017/320069 ,  A61B2017/32007 ,  A61B2018/00023 ,  A61B2018/0022 ,  A61B2018/00494 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00875 ,  A61B18/02 ,  A61B18/042 ,  A61B2018/046 ,  A61B18/1815 ,  A61B2018/20351 ,  A61B2018/2255

摘要： Methods, systems and devices for treating a patient include providing a tissue treatment element constructed and arranged to deliver energy to tissue and treating tissue of the gastrointestinal tract by causing the tissue treatment element to deliver energy to an energy delivery zone. Treatment results in a reduction in the luminal surface area of at least a portion of the gastrointestinal tract. In particular embodiments, the methods, systems and devices are used to treat diabetes.

公开(公告)号：US20240277397A1

公开(公告)日：2024-08-22

申请号：US18650342

申请日：2024-04-30

申请人： Apyx Medical Corporation

发明人： John Andres ,  Shawn D Roman

IPC分类号： A61B18/12 ,  A61B18/00 ,  A61B18/04 ,  A61B18/14

CPC分类号： A61B18/1206 ,  A61B18/042 ,  A61B18/14 ,  A61B2018/00178 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00601 ,  A61B2018/00702 ,  A61B2018/1253 ,  A61B2018/126

摘要： Devices, systems and methods are provided for subdermal tissue tightening through soft tissue coagulation and for use in cosmetic surgery applications. The devices, systems and methods of the present disclosure may be used for a minimally invasive application of helium-based cold plasma energy to subcutaneous tissue for the purpose of tightening lax tissue.

公开(公告)号：US12064160B2

公开(公告)日：2024-08-20

申请号：US17982153

申请日：2022-11-07

申请人： Clear Intradermal Technologies, Inc.

发明人： James W. Winkelman ,  Martin E. Schmieg

IPC分类号： A61N1/44 ,  A61B18/04 ,  A61B18/14 ,  A61Q1/14 ,  A61B17/00 ,  A61B18/00

CPC分类号： A61B18/042 ,  A61B18/1477 ,  A61Q1/145 ,  A61B2017/00769 ,  A61B2017/00973 ,  A61B2018/0016 ,  A61B2018/00166 ,  A61B2018/00196 ,  A61B2018/0047 ,  A61B2018/00583 ,  A61B2018/00714 ,  A61B2018/00916 ,  A61B2218/002 ,  A61B2218/007 ,  A61N1/44

摘要： Methods and systems are disclosed for removing a tattoo from a subject's skin by application of a cold plasma that is delivered via a liquid-gas mixture. The plasma can be delivered in the form of gas bubbles, in which at least a portion of gas is in the form of a plasma.

公开(公告)号：US12059190B2

公开(公告)日：2024-08-13

申请号：US17319157

申请日：2021-05-13

申请人： Technion Research & Development Foundation Limited ,  Rambam Med-Tech Ltd.

发明人： Yakov Krasik ,  Joshua Felsteiner ,  Yakov Slutsker ,  Ziv Gil ,  Jacob Cohen ,  Yoav Binenbaum

IPC分类号： H05H1/00 ,  A61B1/018 ,  A61B18/04 ,  H05H1/24 ,  A61B17/00 ,  A61B18/00

CPC分类号： A61B18/042 ,  A61B1/018 ,  H05H1/2406 ,  A61B2017/00039 ,  A61B2017/00057 ,  A61B2017/00061 ,  A61B2018/00791 ,  A61B2018/00982 ,  H05H1/245 ,  H05H1/246 ,  H05H1/2465 ,  H05H2245/32 ,  H05H2245/34

摘要： A system for generating cold plasma is presented, suitable for use in in-vivo treatment of biological tissue. The system comprising: a control unit connectable to an elongated member at a first proximal end of the elongated member. The elongated member comprises a plasma generating unit at a second distal end thereof and gas and electricity transmission channels extending from said first proximal end towards said plasma generating unit. The control unit comprises a gas supply unit configured to provide predetermined flow rate of selected gas composition through said gas transmission channel and a power supply unit configured to generate selected sequence of high-frequency electrical pulses, typically in mega Hertz range, directed through said electricity transmission channel, thereby providing power and gas of said selected composition to the plasma generating unit for generating cold plasma.

公开(公告)号：US20240238031A1

公开(公告)日：2024-07-18

申请号：US18390759

申请日：2023-12-20

申请人： INSIGHTFUL INSTRUMENTS, INC.

发明人： Michael W. WILTBERGER ,  Phillip GOODING ,  Dan E. ANDERSEN

IPC分类号： A61B18/04 ,  A61B18/00 ,  A61B18/14 ,  A61F9/007 ,  H05H1/46

CPC分类号： A61B18/042 ,  A61B2018/0019 ,  A61B2018/00601 ,  A61B2018/144 ,  A61F9/00781 ,  A61F9/0079 ,  H05H1/466 ,  H05H2245/32

摘要： An elongate electrode is configured to flex and generate plasma to incise tissue. An electrical energy source operatively coupled to the electrode is configured to provide electrical energy to the electrode to generate the plasma. A tensioning element is operatively coupled to the elongate electrode. The tensioning element can be configured to provide tension to the elongate electrode to allow the elongate electrode to flex in response to the elongate electrode engaging the tissue and generating the plasma. The tensioning element operatively coupled to the flexible elongate electrode may allow for the use of a small diameter electrode, such as a 5 μm to 20 μm diameter electrode, which can allow narrow incisions to be formed with decreased tissue damage. In some embodiments, the tensioning of the electrode allows the electrode to more accurately incise tissue by decreasing variations in the position of the electrode along the incision path.

公开(公告)号：US20240180605A1

公开(公告)日：2024-06-06

申请号：US18404033

申请日：2024-01-04

申请人： HERMES INNOVATIONS LLC

发明人： AKOS TOTH ,  CSABA TRUCKAI

IPC分类号： A61B18/04 ,  A61B18/00 ,  A61B18/12 ,  A61B18/14

CPC分类号： A61B18/042 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2018/00577 ,  A61B2018/00589 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/122

摘要： Tissue is treated using a radiofrequency power supply connected to an applicator having a chamber filled with an electrically non-conductive gas surrounded by a thin dielectric wall. A radiofrequency voltage is applied at a level sufficient to ionize the gas into a plasma and to capacitively couple the ionized plasma with the tissue to deliver radiofrequency current to ablate or otherwise treat the tissue.

公开(公告)号：US20240138756A1

公开(公告)日：2024-05-02

申请号：US18409179

申请日：2024-01-10

申请人： MINERVA SURGICAL, INC.

发明人： AKOS TOTH ,  ROBIN BEK ,  DOMINIQUE FILLOUX

IPC分类号： A61B5/00 ,  A61B18/04 ,  A61B18/14 ,  A61M13/00 ,  A61M31/00

CPC分类号： A61B5/4325 ,  A61B5/4836 ,  A61B18/042 ,  A61B18/1485 ,  A61M13/003 ,  A61M31/00 ,  A61B2017/4216

摘要： Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

公开(公告)号：US11903722B2

公开(公告)日：2024-02-20

申请号：US17810906

申请日：2022-07-06

申请人： Minerva Surgical, Inc.

发明人： Akos Toth ,  Robin Bek ,  Dominique Filloux

IPC分类号： A61B5/00 ,  A61M25/00 ,  A61B18/04 ,  A61B18/14 ,  A61M31/00 ,  A61M13/00 ,  A61B17/42 ,  A61B18/00

CPC分类号： A61B5/4325 ,  A61B5/4836 ,  A61B18/042 ,  A61B18/1485 ,  A61M13/003 ,  A61M31/00 ,  A61B2017/4216 ,  A61B2018/00214 ,  A61B2018/00559 ,  A61B2018/00577 ,  A61B2018/00821 ,  A61B2018/147 ,  A61B2505/05

摘要： Methods, systems and devices for evaluating the integrity of a uterine cavity. A method comprises introducing transcervically a probe into a patient's uterine cavity, providing a flow of a fluid (e.g., CO2) through the probe into the uterine cavity and monitoring the rate of the flow to characterize the uterine cavity as perforated or non-perforated based on a change in the flow rate.

公开(公告)号：US11903642B2

公开(公告)日：2024-02-20

申请号：US17180738

申请日：2021-02-20

申请人： Bolt Medical, Inc.

发明人： Christopher A. Cook ,  Eric Schultheis

IPC分类号： A61B18/20 ,  A61B18/24 ,  A61B18/04 ,  A61B18/26 ,  A61B18/22 ,  A61B18/00

CPC分类号： A61B18/245 ,  A61B18/042 ,  A61B18/26 ,  A61B2018/0022 ,  A61B2018/00369 ,  A61B2018/00386 ,  A61B2018/204 ,  A61B2018/2015 ,  A61B2018/2035 ,  A61B2018/20361 ,  A61B2018/2288

摘要： A method for treating a treatment site within or adjacent to a vessel wall or a heart valve, includes the steps of (i) generating light energy with a light source; (ii) positioning a balloon substantially adjacent to the treatment site, the balloon having a balloon wall that defines a balloon interior that receives a balloon fluid; (iii) receiving the light energy from the light source with a light guide at a guide proximal end; (iv) guiding the light energy with the light guide in a first direction from the guide proximal end toward a guide distal end that is positioned within the balloon interior; and (v) optically analyzing with an optical analyzer assembly light energy from the light guide, wherein the light energy that is analyzed moves in a second direction that is opposite the first direction.