公开(公告)号：US10421814B2

公开(公告)日：2019-09-24

申请号：US15883130

申请日：2018-01-30

Applicant: UCB BIOPHARMA SPRL

Inventor： Graham Craggs ,  Karine Jeannine Madeleine Herve ,  Diane Marshall

IPC: C07K16/28 ,  C07K16/00 ,  A61K38/18 ,  A61K39/00

Abstract: The present invention relates to an anti-CSF-1R antibody and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of expressing the antibody or binding fragment in a host cell. The present invention also extends to pharmaceutical compositions comprising the antibody or a binding fragment thereof and use of the antibody, binding fragment and compositions comprising the same in treatment.

公开(公告)号：US09908939B2

公开(公告)日：2018-03-06

申请号：US14914676

申请日：2014-08-26

Applicant: UCB BIOPHARMA SPRL

Inventor： Graham Craggs ,  Karine Jeannine Madeleine Hervé ,  Diane Marshall

IPC: C07K16/28 ,  C07K16/00 ,  C12P21/08 ,  A61K39/00

CPC classification number: C07K16/2866 ,  A61K2039/505 ,  C07K2317/24 ,  C07K2317/33 ,  C07K2317/565 ,  C07K2317/76 ,  C07K2317/92 ,  C07K2317/94

Abstract: The present invention relates to an anti-CSF-1R antibody and binding fragments thereof, DNA encoding the same, host cells comprising said DNA and methods of expressing the antibody or binding fragment in a host cell. The present invention also extends to pharmaceutical compositions comprising the antibody or a binding fragment thereof and use of the antibody, binding fragment and compositions comprising the same in treatment.