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公开(公告)号：US10344081B2
公开(公告)日：2019-07-09
申请号：US15742070
申请日：2016-07-05
申请人： UCB BIOPHARMA SPRL
发明人： Kerry Louise Tyson , Terence Seward Baker , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade , David Edward Ormonde Knight
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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公开(公告)号：US10889640B2
公开(公告)日：2021-01-12
申请号：US16409945
申请日：2019-05-13
申请人： UCB BIOPHARMA SPRL
发明人： David Edward Ormonde Knight , Terence Seward Baker , David James McMillan , Robert Anthony Griffin , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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公开(公告)号：US10287343B2
公开(公告)日：2019-05-14
申请号：US15742087
申请日：2016-07-05
申请人： UCB BIOPHARMA SPRL
发明人： David Edward Ormonde Knight , Terence Seward Baker , David James McMillan , Robert Anthony Griffin , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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公开(公告)号：US20160367560A1
公开(公告)日：2016-12-22
申请号：US15185948
申请日：2016-06-17
申请人： UCB Biopharma SPRL
IPC分类号： A61K31/522 , A61K9/20 , A61K31/454
CPC分类号： A61K31/522 , A61K9/20 , A61K31/195 , A61K31/198 , A61K31/423 , A61K31/445 , A61K31/451 , A61K31/454 , A61K31/495 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/519 , A61K31/52 , A61K31/5377 , A61K31/5415 , A61K45/06 , A61K2300/00
摘要： The invention pertains to a method of treating Parkinson's disease (PD) in a mammal, comprising administering a first pharmaceutical agent and a second pharmaceutical agent, wherein the first pharmaceutical agent is an antagonist of the adenosine receptor 2 (A2A) and the second pharmaceutical agent is an antagonist of the N-methyl-D-aspartate (NMDA) receptor subtype NR2B.
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