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公开(公告)号：US20200377578A1
公开(公告)日：2020-12-03
申请号：US16919576
申请日：2020-07-02
申请人： UCB Biopharma SPRL
发明人： David Paul Humphreys , Daniel John Lightwood , Kerry Louise Tyson , David Edward Ormonde Knight , Karine Jeannine Madeleine Hervé , Joanne Elizabeth Compson , Matthew Jon Timothy Page , Andrew Charles Payne , Nicola Louise Fisher , Brendon MacKenzie , Matthew Cox
IPC分类号： C07K16/12 , A61K39/40 , A61K45/06 , G01N33/569 , G01N33/573 , G01N33/68
摘要： This present invention describes the derivation and selection of antibodies capable of neutralising the major exotoxins; TcdA and TcdB of Clostridium difficile. The invention also describes novel neutralisation and antigen binding properties of individual Mabs and mixtures thereof.
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公开(公告)号：US10344081B2
公开(公告)日：2019-07-09
申请号：US15742070
申请日：2016-07-05
申请人： UCB BIOPHARMA SPRL
发明人： Kerry Louise Tyson , Terence Seward Baker , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade , David Edward Ormonde Knight
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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公开(公告)号：US10889640B2
公开(公告)日：2021-01-12
申请号：US16409945
申请日：2019-05-13
申请人： UCB BIOPHARMA SPRL
发明人： David Edward Ormonde Knight , Terence Seward Baker , David James McMillan , Robert Anthony Griffin , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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公开(公告)号：US10287343B2
公开(公告)日：2019-05-14
申请号：US15742087
申请日：2016-07-05
申请人： UCB BIOPHARMA SPRL
发明人： David Edward Ormonde Knight , Terence Seward Baker , David James McMillan , Robert Anthony Griffin , Georges Mairet-Coello , Patrick Downey , Jean-Philippe Courade
摘要： The present invention relates to Tau-binding antibodies and binding fragments thereof.
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