公开(公告)号：US20200369675A1

公开(公告)日：2020-11-26

申请号：US16767896

申请日：2018-11-27

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Macquire

IPC: C07D491/048 ,  C07B59/00 ,  A61K51/04

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.

公开(公告)号：US20220162221A1

公开(公告)日：2022-05-26

申请号：US17534711

申请日：2021-11-24

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Maquire

IPC: C07D491/048 ,  A61K51/04 ,  C07B59/00

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.

公开(公告)号：US11312716B2

公开(公告)日：2022-04-26

申请号：US16749537

申请日：2020-01-22

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Laurent Provins ,  Celine Vermeiren ,  Yogesh Anil Sabnis

IPC: C07D471/14 ,  A61K31/437 ,  A61K51/04 ,  C07B59/00

Abstract: The invention relates to 9H-pyrrolo-dipyridine derivatives of formula I, processes for preparing them, pharmaceutical compositions containing them and their use as radiopharmaceuticals in particular as imaging agents for the detection of Tau aggregates.

公开(公告)号：US20240343737A1

公开(公告)日：2024-10-17

申请号：US18632964

申请日：2024-04-11

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Anne Valade ,  Celine Vermeiren ,  Martyn Wood ,  Ralph Macquire

IPC: C07D491/048 ,  A61K51/04 ,  C07B59/00

CPC classification number: C07D491/048 ,  A61K51/0459 ,  C07B59/002 ,  C07B2200/05

Abstract: The present invention relates to radiolabelled 4-(furo[3,2-c]pyridin-4-yl) derivatives and their use as radioactive tracers, and in particular their use as imaging agents.

公开(公告)号：US20210047326A1

公开(公告)日：2021-02-18

申请号：US16749537

申请日：2020-01-22

Applicant: UCB Biopharma SRL

Inventor： Joel Mercier ,  Laurent Provins ,  Celine Vermeiren ,  Yogesh Anil Sabnis

IPC: C07D471/14 ,  A61K51/04 ,  C07B59/00

Abstract: The invention relates to 9H-pyrrolo-dipyridine derivatives of formula I, processes for preparing them, pharmaceutical compositions containing them and their use as radiopharmaceuticals in particular as imaging agents for the detection of Tau aggregates.