公开(公告)号：US20220162227A1

公开(公告)日：2022-05-26

申请号：US17539715

申请日：2021-12-01

申请人： UNION therapeutics A/S

发明人： Allan Carsten Dahl ,  Johan Eriksson Bajtner ,  Esben Paul Krogh Olsen ,  Bjørn Metzler

IPC分类号： C07D495/10 ,  B01J21/16

摘要： The present invention relates to novel methods for the preparation of 1,3-benzodioxole heterocyclic compounds. The compounds are useful as PDE4 inhibitors.

公开(公告)号：US12084457B2

公开(公告)日：2024-09-10

申请号：US17539715

申请日：2021-12-01

申请人： UNION therapeutics A/S

发明人： Allan Carsten Dahl ,  Johan Eriksson Bajtner ,  Esben Paul Krogh Olsen ,  Bjørn Metzler

IPC分类号： C07D495/10 ,  B01J21/16

CPC分类号： C07D495/10 ,  B01J21/16 ,  C07B2200/13

摘要： The present invention relates to novel methods for the preparation of 1,3-benzo-dioxole heterocyclic compounds. The compounds are useful as PDE4 inhibitors.

公开(公告)号：US11220514B2

公开(公告)日：2022-01-11

申请号：US16624491

申请日：2018-06-19

申请人： UNION therapeutics A/S

发明人： Allan Carsten Dahl ,  Johan Eriksson Bajtner ,  Esben Paul Krogh Olsen ,  Bjørn Metzler

IPC分类号： C07D495/10 ,  B01J21/16

摘要： The present invention relates to novel methods for the preparation of 1,3-benzodioxole heterocyclic compounds of formula (I). The compounds are useful as PDE4 inhibitors.