公开(公告)号：US11566133B2

公开(公告)日：2023-01-31

申请号：US16310780

申请日：2017-06-19

申请人： UNIVERSIDAD DE LOS ANDES ,  CELLS FOR CELLS S.A.

发明人： Javier Enrione Cáceres ,  Paulo Díaz-Calderón ,  Alessandro Zaupa ,  Juan Pablo Acevedo Cox

IPC分类号： C08L89/06 ,  C07K14/78 ,  C08H1/00 ,  C08J3/075 ,  C08K5/101 ,  C07K14/46 ,  B33Y70/00

摘要： The present invention refers to a composition comprising a solution which in turn comprises an amino acidic chain gelatin polymer derived from natural sources of cold-adapted marine species, at a concentration from 1% to 20% (w/v), which optionally further comprises a polymerizing initiator such as a photoinitiator, and is chemically functionalized to become reactive to polymerization or crosslinking in presence of free radicals. This composition is especially useful for 3D printing, extrusion systems (additive fabrication), spray systems, casting, micro- and nano fibers fabrication systems (electrospinning, solution blow spinning) or microfluidics.

公开(公告)号：US10766029B2

公开(公告)日：2020-09-08

申请号：US15551007

申请日：2016-02-22

申请人： CELLS FOR CELLS S.A.

发明人： Juan Pablo Acevedo Cox

IPC分类号： B01L3/00 ,  G01N33/50

摘要： Devices are for assessing the migration response in the presence of a stable encapsulated gradient of a factor or factor combination, and quantifying the adherence response inside micro-channels in the presence of different factors. A platform is for obtaining information relating to migration score or the quantification of adhered cells through use of the devices, and it allows this information to be used to assess therapeutic potential. A method quantifies the cells migration response and the cell adherence response.