公开(公告)号：US20180209881A1

公开(公告)日：2018-07-26

申请号：US15742532

申请日：2015-07-06

Applicant: UNIVERSITÄT BASEL

Inventor： Stefan Alexander ARNOLD ,  Thomas BRAUN ,  Henning STAHLBERG

IPC: G01N1/42 ,  H01J37/20

CPC classification number: G01N1/42 ,  H01J37/20

Abstract: The invention relates to a preparation system for preparing a sample for electron microscopy, comprising:—a liquid handling system (0) comprising a dispensing head (1), wherein said liquid handling system (0) is configured to aspirate and dispense a volume of a sample via the dispensing head (1),—a support structure (2) that is configured to accommodate the sample, a temperature-controlled stage (4) that is configured to keep said support structure (2) at a pre-defined temperature when the support structure (2) is arranged on the temperature-controlled stage (4), a first adapter (3) configured to hold said support structure (2), a transfer mechanism (60) that is configured to be connected to the first adapter (3) holding the support structure (2) and to move said support structure (2) into a container (8) containing a liquid cryogen (80) so that the sample on the support structure (2) contacts the cryogen (80). Furthermore, the invention relates to a corresponding method.