公开(公告)号：US20220296875A1

公开(公告)日：2022-09-22

申请号：US17835132

申请日：2022-06-08

Applicant: HIGHDIM GMBH ,  Universitätsspital Basel

Inventor： Oleksii Morozov ,  Patrick Hunziker

IPC: A61M60/50 ,  A61B5/00 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/029 ,  A61B5/05 ,  A61B8/06 ,  A61M60/135 ,  A61M60/871

Abstract: The present invention relates to systems, methods and algorithms for determination of heart pump function and their use in livings subject are described.
The invention further relates to complementary parts of such systems that work best in combination.
Medical catheters, sheaths and shafts are disclosed that carry an arrangement of integrated digital sensor systems-on-chip (SoC) in the portion thereof residing inside the body. These devices combine at their portion that resides inside the body, the complete chain of signal transduction, signal analog-to-digital conversion and digital signal transmission, and allow to acquire single and multiple physical entities in a single setup. In specific instances the devices integrate wireless data transfer functionality, and in specific instances they integrate wireless energy harvesting for battery-free functionality.
The present invention further describes complementary monitor systems that are suited for reception, processing and analysis of data acquired by such catheters/sheaths/shafts to yield a robust assessment of cardiac performance.
Moreover, the present invention relates to innovations which render such systems applicable to patients with and without cardiac assist devices.

公开(公告)号：US10513585B2

公开(公告)日：2019-12-24

申请号：US15539490

申请日：2015-12-23

Applicant: UNIVERSITÄTSSPITAL BASEL

Inventor： Patrick Hunziker ,  Kegang Liu

IPC: C08G77/452 ,  A61K49/00 ,  A61K9/00 ,  A61K47/34 ,  A61K9/107 ,  A61K47/55 ,  A61K47/59 ,  A61K47/69 ,  A61K31/337 ,  A61K31/519 ,  A61K31/704 ,  A61K31/713

Abstract: The preparation of poly-2-oxazoline amphiphilic polymers and copolymers is described. Self-assembled particles comprising these amphiphilic polymers and which are useful for the targeted delivery of therapeutic and diagnostic agents are also described.

公开(公告)号：US20190381226A1

公开(公告)日：2019-12-19

申请号：US16479438

申请日：2018-01-19

Applicant: HIGHDIM GMBH ,  Universitätsspital Basel

Inventor： Oleksii Morozov ,  Patrick Hunziker

IPC: A61M1/10 ,  A61B5/0205 ,  A61B5/01 ,  A61M1/12 ,  A61B5/00 ,  A61B5/029 ,  A61B5/05 ,  A61B8/06

Abstract: The present invention relates to systems, methods and algorithms for determination of heart pump function and their use in livings subject are described.The invention further relates to complementary parts of such systems that work best in combination.Medical catheters, sheaths and shafts are disclosed that carry an arrangement of integrated digital sensor systems-on-chip (SoC) in the portion thereof residing inside the body. These devices combine at their portion that resides inside the body, the complete chain of signal transduction, signal analog-to-digital conversion and digital signal transmission, and allow to acquire single and multiple physical entities in a single setup. In specific instances the devices integrate wireless data transfer functionality, and in specific instances they integrate wireless energy harvesting for battery-free functionality.The present invention further describes complementary monitor systems that are suited for reception, processing and analysis of data acquired by such catheters/sheaths/shafts to yield a robust assessment of cardiac performance.Moreover, the present invention relates to innovations which render such systems applicable to patients with and without cardiac assist devices.