公开(公告)号：US20200063099A1

公开(公告)日：2020-02-27

申请号：US16462965

申请日：2017-11-23

申请人： UNIVERSITÉ DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT D'OPTIQUE GRADUATE SCHOOL

发明人： MAXIME FEYEUX ,  KEVIN ALESSANDRI ,  PIERRE NASSOY ,  LAURENT COGNET ,  ABDELHAMID BENAZZOUZ ,  ERWAN BEZARD

IPC分类号： C12N5/0793 ,  C12N5/00 ,  A61K35/30

摘要： The invention relates to a neural tissue unit for use in implantation into the nervous system of a human or non-human mammal, wherein said neural tissue unit contains differentiated post-mitotic neuronal cells in an extracellular matrix, said unit being obtained from a cellular microcompartment comprising a hydrogel capsule surrounding the neural tissue unit, and said hydrogel capsule being at least partially removed before use of the neural tissue unit. The invention also relates to a process for preparing such a neural tissue unit.

公开(公告)号：US20230257699A1

公开(公告)日：2023-08-17

申请号：US18124921

申请日：2023-03-22

申请人： UNIVERSITE DE BORDEAUX ,  CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ,  INSTITUT D'OPTIQUE THEORIQUE ET APPLIQUEE

发明人： MAXIME FEYEUX ,  KEVIN ALLESSANDRI ,  PIERRE NASSOY ,  LAURENT COGNET ,  ABDELHAMID BENAZZOUZ ,  ERWAN BEZARD

IPC分类号： C12N5/0793 ,  A61K35/30 ,  C12N5/00

CPC分类号： C12N5/0619 ,  A61K35/30 ,  C12N5/0012 ,  C12N2501/39 ,  C12N2501/42 ,  C12N2506/45

摘要： The invention relates to a neural tissue unit for use in implantation into the nervous system of a human or non-human mammal, wherein said neural tissue unit contains differentiated post-mitotic neuronal cells in an extracellular matrix, said unit being obtained from a cellular microcompartment comprising a hydrogel capsule surrounding the neural tissue unit, and said hydrogel capsule being at least partially removed before use of the neural tissue unit. The invention also relates to a process for preparing such a neural tissue unit.