专利检索 ap:("UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC)" OR "CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE") AND inv:"Florian SENNLAUB" 第 1 页

1.

发明申请
AGENTS FOR USE IN THE TREATMENT OF RETINAL INFLAMMATION 审中-公开
标题翻译：用于治疗感染性炎症的药剂

公开(公告)号：US20160340424A1

公开(公告)日：2016-11-24

申请号：US15111986

申请日：2015-01-22

申请人： UNIVERSITÉ PIERRE ET MARIE CURIE - PARIS 6 (UPMC) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

发明人： Florian SENNLAUB , Xavier GUILLONNEAU , Olivier LEVY , José-Alain SAHEL

IPC分类号： C07K16/24 , C07K16/28

CPC分类号： C07K16/248 , A61K45/00 , C07K16/2866 , C07K2317/76

摘要： The present invention relates to preventive and/or therapeutic agents for use in the treatment of retinal inflammation, and more specifically of Age-related macular degeneration and Retinitis pigmentosa, wherein said agents are selected from an IL-6 inhibitor, an APOE inhibitor and/or a Fas activator as an active ingredient.

摘要翻译： 本发明涉及用于治疗视网膜炎症的预防和/或治疗剂，更具体地涉及年龄相关性黄斑变性和色素性视网膜炎，其中所述药剂选自IL-6抑制剂，APOE抑制剂和/ 或Fas活化剂作为活性成分。

2.

发明申请
AGENTS THAT INHIBIT THE BINDING OF CFH TO CD11b/CD18 AND USES THEREOF 审中-公开

公开(公告)号：US20190010235A1

公开(公告)日：2019-01-10

申请号：US16066015

申请日：2016-12-23

申请人： SORBONNE UNIVERSITE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSERM (Institut National de la Santé et de la Recherche Médicale)

发明人： Florian SENNLAUB , Bertrand CALLIPPE , Xavier GUILLONNEAU , José-Alain SAHEL

IPC分类号： C07K16/28 , A61P29/00 , A61P27/02 , A61K9/00

摘要： Disclosed are agents inhibiting the interaction between CFH and CD11b/18, as well as the use of such agents, in particular for treating inflammatory disorders, such as age-related macular degeneration.

3.

发明公开
AN INSULIN SENSITIZER FOR USE IN THE PREVENTION AND/OR TREATMENT OF THE DAMAGES CAUSED BY RETINAL DETACHMENT 审中-公开

公开(公告)号：US20230172919A1

公开(公告)日：2023-06-08

申请号：US17913268

申请日：2021-03-26

申请人： SORBONNE UNIVERSITE , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE) , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE

发明人： Florian SENNLAUB , Jean-Baptiste CONART , José-Alain SAHEL

IPC分类号： A61K31/4439 , A61K9/00 , A61P27/02 , A61K45/06 , A61K31/155

CPC分类号： A61K31/4439 , A61K9/0019 , A61K9/0048 , A61K31/155 , A61K45/06 , A61P27/02

摘要： An insulin sensitizer for use in the prevention and/or treatment of the damages caused by retinal detachment, and in particular for preventing or treating the loss of vision induced by retinal detachment. Also, a composition including the insulin sensitizer for use in the prevention and/or treatment of the damages caused by retinal detachment and a device including the composition.

4.

发明申请
AGENTS THAT ACTIVATE CD47 AND THEIR USE IN THE TREATMENT OF INFLAMMATION 审中-公开

公开(公告)号：US20190225649A1

公开(公告)日：2019-07-25

申请号：US16300438

申请日：2017-05-10

申请人： SORBONNE UNIVERSITE , CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE , INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE)

发明人： Florian SENNLAUB , Michael HOUSSET , Xavier GUILLONNEAU , José-Alain SAHEL , Philippe KAROYAN

IPC分类号： C07K7/08 , A61P29/00 , A61P27/02

摘要： Disclosed are agents activating CD47 and their use in the treatment of inflammation, in particular non-resolving low grade inflammation, characterized by chronic MP infiltration, such as age-related macular degeneration. Also disclosed are pharmaceutical compositions, medicaments and kits including the agents.