专利检索 ap:("UNIVERSITY OF MYSORE" OR "NATIONAL UNIVERSITY OF SINGAPORE" OR "BANGALORE UNIVERSITY" OR "CAMBRIDGE ENTERPRISE LTD") AND inv:"Xiaoyun Dai" 第 1 页

1.

发明授权
Compounds as modulator of JAK-STAT pathway, methods and applications thereof 有权

公开(公告)号：US09604974B2

公开(公告)日：2017-03-28

申请号：US15004114

申请日：2016-01-22

申请人： UNIVERSITY OF MYSORE , NATIONAL UNIVERSITY OF SINGAPORE , BANGALORE UNIVERSITY , CAMBRIDGE ENTERPRISE LTD

发明人： Kanchugarakoppal Subbegowda Rangappa , Basappa , Chakrabhavi Dhananjaya Mohan , Shobith Rangappa , Hanumantharayappa Bharathkumar , Gautam Sethi , Andreas Bender , Peter Edward Lobie , Kam Man Hui , Alan Prem Kumar , Vijay Kumar Pandey , Julian Fuchs , Muthu Kumaraswamy Shanmugam , Krishna Bulusu , Xiaoyun Dai , Feng Li , Amudha Deivasigamani

IPC分类号： C07D413/04 , C07D265/16

CPC分类号： C07D413/04 , C07D265/16

摘要： The present disclosure relates to compound of structural Formula I and a method for preparing said compounds. The disclosure further relates to a method of employing the Formula I compounds for modulation of Janus kinase-Signal Transducer and Activator of Transcription (JAK-STAT) pathway in cancer cells, and the corresponding use of compound of Formula I as anti-cancer agents.