公开(公告)号：US20160281123A1

公开(公告)日：2016-09-29

申请号：US15035747

申请日：2014-11-18

Applicant: UNIVERSITY OF SEOUL INDUSTRY COOPERATION FOUNDATION

Inventor： Jong-Bum LEE ,  Dae-Hoon HAN

IPC: C12P19/34 ,  C12N15/10

CPC classification number: C12P19/34 ,  C12N15/10 ,  C12N15/1003

Abstract: Disclosed are a method of manufacturing an RNA membrane and an RNA membrane manufactured thereby, wherein the RNA membrane can be produced at lower cost, in which the RNA membrane is composed exclusively of RNA, and thus has no toxicity in vivo, is controllable, and can be effectively applied to bio-organs such as the pericardium, as well as the production of peptides or proteins, and particularly, long linear RNA strands, which have not yet formed particles, are concentrated on the surface of a tube by inducing an evaporation process to thus activate the bonding of base pairs thereof, and the roughness and thickness of the RNA membrane can be controlled by changing the manufacturing conditions.

Abstract translation: 公开了制造由此制备的RNA膜和RNA膜的方法，其中RNA膜可以以较低的成本生产，其中RNA膜仅由RNA组成，因此在体内没有毒性，是可控的，以及 可以有效地应用于诸如心包膜的生物器官，以及肽或蛋白质的生产，特别是尚未形成颗粒的长线型RNA链通过诱导蒸发而浓缩在管的表面上 从而激活其碱基对的键合，并且可以通过改变制造条件来控制RNA膜的粗糙度和厚度。