公开(公告)号：US20240294925A1

公开(公告)日：2024-09-05

申请号：US18594910

申请日：2024-03-04

申请人： University of South Florida

发明人： Subhra MOHAPATRA ,  Shyam MOHAPATRA ,  Courtney PENN

IPC分类号： C12N15/113 ,  A61K35/28 ,  A61K45/06 ,  A61K47/69 ,  A61P27/16

CPC分类号： C12N15/1138 ,  A61K35/28 ,  A61K45/06 ,  A61K47/6929 ,  A61P27/16 ,  C12N2310/122 ,  C12N2310/14

摘要： Methods are disclosed for auditory dysfunction by administration of a therapeutic agent and stem cells. The therapeutic agent is chosen from disclosed agents that target the CCL20-CCR6 axis. Further disclosed are treatment protocols of said therapeutic agent and stem cells. The method of treatment is disclosed to be treatment following a traumatic brain injury.

公开(公告)号：US20240293432A1

公开(公告)日：2024-09-05

申请号：US18594989

申请日：2024-03-04

申请人： UNIVERSITY OF SOUTH FLORIDA

发明人： Subhra MOHAPATRA ,  Shyam MOHAPATRA ,  Ryan Green

IPC分类号： A61K31/00 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61P35/00

CPC分类号： A61K31/658 ,  A61K31/506 ,  A61K31/519 ,  A61K31/5377 ,  A61P35/00

摘要： A composition including a cannabinoid and an anti-cancer agent and methods of treating lung cancer using said composition.

公开(公告)号：US20240293430A1

公开(公告)日：2024-09-05

申请号：US18594305

申请日：2024-03-04

申请人： University of South Florida

发明人： Subhra Mohapatra ,  Shyam MOHAPATRA ,  Roukiah Khalil

IPC分类号： A61K31/585 ,  A61K39/395 ,  A61P35/00

CPC分类号： A61K31/585 ,  A61K39/3955 ,  A61P35/00

摘要： The present disclosure provides methods of treating cancer in a subject in need thereof comprising administering to the subject a therapeutically effective amount of withaferin A and an immune checkpoint blocker. Further, the cancer to be treated may be resistant, have developed resistance, or may be susceptible to resistance to treatment with the immune checkpoint blocker alone or in combination with another therapeutic agent other than withaferin A.

公开(公告)号：US20220409765A1

公开(公告)日：2022-12-29

申请号：US17850791

申请日：2022-06-27

申请人： University of South Florida

发明人： Dmitri VORONIN ,  Shyam MOHAPATRA ,  Subhra MOHAPATRA ,  Sharad AMBARDAR ,  Mark HOWELL ,  Karthick MAYILSAMY

IPC分类号： A61L9/20 ,  A61L2/10

摘要： Method for increasing efficiency of a pathogen inactivation via enhancing UVC light absorption at such pathogen by multiple diffuse scattering of the light at a wall defining a substantially closed volume, thereby increasing a number of angles at which the pathogen is being irradiate as compared with a direct irradiation of the pathogen with a beam of such light.

公开(公告)号：US20220349878A1

公开(公告)日：2022-11-03

申请号：US17733265

申请日：2022-04-29

申请人： University of South Florida

发明人： Subhra MOHAPATRA ,  Shyam MOHAPATRA ,  Ryan GREEN

IPC分类号： G01N33/53 ,  G01N33/543 ,  B01L3/00

摘要： The present disclosure provides novel gravitational flow assays for detecting an antigen in a biological sample using DNA-capture sequences. Specifically, gravitational flow assays and methods of detecting viruses, including coronaviruses, are provided.