公开(公告)号：US20230159979A1

公开(公告)日：2023-05-25

申请号：US17904916

申请日：2021-04-15

Applicant: UNIVERSITY OF WASHINGTON ,  LAMPROGEN, INC.

Inventor： Daniel T. Chiu ,  Haobin Chen ,  Jiangbo Yu

IPC: C12Q1/32 ,  C12Q1/00 ,  C09K11/06 ,  C09K11/02

CPC classification number: C12Q1/32 ,  C12Q1/008 ,  C09K11/06 ,  C09K11/025 ,  B82Y20/00

Abstract: Transducers, kits, systems, and methods for determining a concentration of an analyte are described. In an embodiment, the transducers include a chromophore; and an enzyme physically associated with the chromophore. In an embodiment, the transducer is configured to catalyze a reaction comprising a plurality of reaction elements. In an embodiment, the plurality of reaction elements comprises one or more reactants including the analyte and one or more products. In an embodiment, an amount of fluorescence emitted from the chromophore is determined by a concentration of a reaction element of the plurality of reaction elements.