专利检索 ap:("UNIVERSITY OF WASHINGTON" OR "THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY") AND inv:"Kevin Jude" 第 1 页

1.

发明公开
De Novo Design of Potent and Selective Interleukin Mimetics 审中-公开

公开(公告)号：US20240076342A1

公开(公告)日：2024-03-07

申请号：US18187639

申请日：2023-03-21

申请人： UNIVERSITY OF WASHINGTON , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

发明人： Daniel Adriano Silva Manzano , Shawn Yu , Umut Ulge , David Baker , Kenan Christopher Garcia , Jamie Spangler , Carl Walkey , Alfredo Quijano Rubio , Kevin Jude , Brian Weitzner

IPC分类号： C07K14/55 , A61K47/60 , A61K47/62 , C07K14/54

CPC分类号： C07K14/55 , A61K47/60 , A61K47/62 , C07K14/5406 , C07K14/5437 , C07K14/5443 , A61K38/00

摘要： De novo designed polypeptides that bind to IL-2 receptor βγc heterodimer (IL-2Rβγc), IL-4 receptor αγc heterodimer (IL-4Rαγc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.

2.

发明申请
De Novo Design of Potent and Selective Interleukin Mimetics 审中-公开

公开(公告)号：US20200339648A1

公开(公告)日：2020-10-29

申请号：US16905669

申请日：2020-06-18

申请人： UNIVERSITY OF WASHINGTON , THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY

发明人： Daniel Adriano Silva Manzano , Shawn Yu , Umut Ulge , David Baker , Kenan Christopher Garcia , Jamie Spangler , Carl Walkey , Alfredo Quijano Rubio , Kevin Jude , Brian Weitzner

IPC分类号： C07K14/55 , C07K14/54 , A61K47/62 , A61K47/60

摘要： De novo designed polypeptides that bind to IL-2 receptor βνc heterodimer (IL-2Rβνc), IL-4 receptor ανc heterodimer (IL-4Rανc), or IL-13 receptor α subunit (IL-13Rα) are disclosed, as are methods for using and designing the polypeptides.