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1.6alpha-fluoro-16-methyl - 4 - pregnene 3,20-diones and intermediates produced in the synthesis thereof 失效
Title translation: 6ALPHA-FLUORO-16-METHYL-4-PREGNENE 3,20-DIONES和其中合成的中间体公开(公告)号:US3557158A
公开(公告)日:1971-01-19
申请号:US3557158D
申请日:1962-01-22
Applicant: UPJOHN CO
Inventor: LINCOLN FRANK H , SCHNEIDER WILLIAM P , SPERO GEORGE B
IPC: C07J5/00 , C07J75/00 , C07C169/32
Abstract: THIS INVENTION RELATES TO CERTAIN NOVEL STEROIDS, MNORE PARTICULARLY TO 6A-FLUORO-11B,17A, 21-TRIHYDROXY-16-METHYL4-PREGNENE-3,20-DIONE, 6A-FLUORO-17A,21-DIHYDROXY-16 METHYL-4-PREGNENE-3,11,20-TIONE, 6A-FLUORO-11B,17A,21TRIHYDROXY - 16 - METHYL - 1,4 - PREGNADIENE -3,20 - DIONE, 6A-FLUORO-17A, 21-DIHYDROXY - 16 - METHYL - 1,4 PREGNADIENE-3,11, 20-TRIONE, THE 9A-HALO, ESPECIALLY THE 9AFLUORO, COMPOUNDS CORRESPONDING OTHER WISE THERETO, 21ESTERS EACH, THE CORRESPONDING 21-FLUORO AND 21-DESOXY COMPOUNDS, AND INTERMEDIATES IN THE PRODUCTION THEREOF.
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2.Method of controlling reproductive cycle with 6alpha - methyl - 17alpha hydroxyprogesterone 17-acetate 失效
Title translation: 用6ALPHA-METHYL-17ALPHA羟丙基甲硅烷酮17-醋酸盐控制生殖周期的方法公开(公告)号:US3444296A
公开(公告)日:1969-05-13
申请号:US3444296D
申请日:1960-06-28
Applicant: UPJOHN CO
Inventor: SPERO GEORGE B
CPC classification number: A61K9/0053 , A23K20/168 , A23K20/184
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公开(公告)号:US3296254A
公开(公告)日:1967-01-03
申请号:US17027562
申请日:1962-01-31
Applicant: UPJOHN CO
Inventor: SPERO GEORGE B
CPC classification number: C07J71/00 , C07J75/00 , Y10S435/939
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4.6alpha-methyl-17alpha, 21-dihydroxy-4-pregnene-3, 20-dione and 21-acetate 失效
Title translation: 6α-甲基-17α,21-二羟基-4-孕烯-3,20-二酮和21-乙酸酯-
5.Process for the production of 1 (and 6, 16)-substituted-1-dehydro-11-ketoprogesterones and intermediates therefor 失效
Title translation: 制备1(和6,16) - 取代-1-脱氢-11-酮基孕酮的方法及其中间体-
6.21-organic sulfonates of 11, 17, 21-trioxygenated-3-keto pregnenes 失效
Title translation: 11,17,21-三氧化-3-酮孕烯的21-有机磺酸盐公开(公告)号:US3105083A
公开(公告)日:1963-09-24
申请号:US2214160
申请日:1960-04-14
Applicant: UPJOHN CO
Inventor: LINCOLN FRANK H , SCHNEIDER WILLIAM P , SPERO GEORGE B
CPC classification number: C07J31/00 , C07J75/00 , Y10S435/832 , Y10S435/843 , Y10S435/866 , Y10S435/872 , Y10S435/874 , Y10S435/899 , Y10S435/911 , Y10S435/929 , Y10S435/939
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7.6-methyl-1-dehydro analogues of cortisone, hydrocortisone and 21-esters thereof 失效
Title translation: 可的松,氢化可的松及其21-酯的6-甲基-1-脱氢类似物公开(公告)号:US2897218A
公开(公告)日:1959-07-28
申请号:US62377656
申请日:1956-11-23
Applicant: UPJOHN CO
Inventor: SEBEK OLDRICH K , SPERO GEORGE B
CPC classification number: C07J5/00 , C07J75/00 , Y10S435/843 , Y10S435/911 , Y10S435/929
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8.6alpha-methyl-11beta,21-dihydroxy-4-pregnene-3-one and 21-hydrocarbon carboxylic acid esters thereof 失效
Title translation: 6α-甲基-11β,21-二羟基-4-孕烯-3-酮和21-烃羧酸酯公开(公告)号:US2883402A
公开(公告)日:1959-04-21
申请号:US75543358
申请日:1958-08-18
Applicant: UPJOHN CO
Inventor: MAGERLEIN BARNEY J , SPERO GEORGE B
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公开(公告)号:US2867634A
公开(公告)日:1959-01-06
申请号:US62382256
申请日:1956-11-23
Applicant: UPJOHN CO
Inventor: LINCOLN JR FRANK H , SCHNEIDER WILLIAM P , SPERO GEORGE B
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