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1.发明授权6 beta-hydroxycortisone 6, 21-diacylate compounds and process for the production thereof 失效6β-羟基可的松6,21-二酰基化合物及其生产方法
公开(公告)号：US2935521A
公开(公告)日：1960-05-03
申请号：US77535858
申请日：1958-11-21
Applicant: UPJOHN CO
Inventor： HANZE ARTHUR R , MURRAY HERBERT C , SEBEK OLDRICH K
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/939
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公开(公告)号：US2838546A
公开(公告)日：1958-06-10
申请号：US71600558
申请日：1958-02-19
Applicant: UPJOHN CO
Inventor： MAGERLEIN BARNEY J , SCHNEIDER WILLIAM P , SEBEK OLDRICH K , SPERO GEORGE B
CPC classification number: C12P33/00 , C07J5/00 , C07J75/00 , Y10S435/886
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公开(公告)号：US2864836A
公开(公告)日：1958-12-16
申请号：US71601958
申请日：1958-02-19
Applicant: UPJOHN CO
Inventor： LINCOLN FRANK H , SCHNEIDER WILLIAM P , SEBEK OLDRICH K , SPERO GEORGE B
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/886
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公开(公告)号：US2838548A
公开(公告)日：1958-06-10
申请号：US71602758
申请日：1958-02-19
Applicant: UPJOHN CO
Inventor： MAGERLEIN BARNEY J , SCHNEIDER WILLIAM P , SEBEK OLDRICH K , SPERO GEORGE B
CPC classification number: C07J5/00 , C07J7/00 , C07J75/00 , C12P33/00 , Y10S435/886
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公开(公告)号：US2838545A
公开(公告)日：1958-06-10
申请号：US71600458
申请日：1958-02-19
Applicant: UPJOHN CO
Inventor： MAGERLEIN BARNEY J , SCHNEIDER WILLIAM P , SEBEK OLDRICH K , SPERO GEORGE B
CPC classification number: C07J5/00 , C07J7/00 , C07J75/00 , C12P33/00 , Y10S435/886
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Patent Agency Ranking
公开(公告)号：US3116220A
公开(公告)日：1963-12-31
申请号：US19021962
申请日：1962-04-26
Applicant: UPJOHN CO
Inventor： SEBEK OLDRICH K
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/911
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7.发明授权
公开(公告)号：US2902411A
公开(公告)日：1959-09-01
申请号：US66862957
申请日：1957-06-28
Applicant: UPJOHN CO
Inventor： MURRAY HERBERT C , SEBEK OLDRICH K
IPC: C12P33/00
CPC classification number: C12P33/00 , Y10S435/818 , Y10S435/911
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公开(公告)号：US2864837A
公开(公告)日：1958-12-16
申请号：US71603558
申请日：1958-02-19
Applicant: UPJOHN CO
Inventor： SEBEK OLDRICH K , SPERO GEORGE B , THOMPSON JOHN L
IPC: C12P33/00
CPC classification number: C12P33/00
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公开(公告)号：US3652536A
公开(公告)日：1972-03-28
申请号：US3652536D
申请日：1969-06-02
Applicant: UPJOHN CO
Inventor： SEBEK OLDRICH K , HOEKSEMA HERMAN
IPC: C12P19/60 , A01N47/18 , A61K31/70 , A61K31/7042 , A61K31/7048 , A61P31/04 , C07D307/73 , C07H17/075 , C08G69/44 , C12P1/06 , C07C47/18
CPC classification number: C07D307/73 , C07H17/075 , C08G69/44 , Y10S435/83
Abstract: ENZYMATIC CLEAVAGE OF THE AMIDE BOND IN THE ANTIBIOTIC NOVOBIOCIN YIELDS NOVENAMINE, A NOVEL COMPOUND, HAVING THE STRUCTURE:
2-(O=),3-(H2N-),4-(HO-),7-((2,2-DI(CH3-),3-(CH3-O-),4-
2H-CHROMENE
(H2N-COO-),5-(HO-)TETRAHYDROPYRAN-6-YL)-O-),8-(CH3-)
NOVENAMINE IS ANIBACTERIALLY ACTIVE AND, THUS CAN BE USED AS AN ANTIBACTERIAL AGENT. FURTHER, IT CAN BE ACYLATED TO FORM NOVEL COMPOUNDS WHICH POSSESS ANTIMICROBIAL PROPERTIES.-
10.发明授权6-methyl-1-dehydro analogues of cortisone, hydrocortisone and 21-esters thereof 失效可的松，氢化可的松及其21-酯的6-甲基-1-脱氢类似物
公开(公告)号：US2897218A
公开(公告)日：1959-07-28
申请号：US62377656
申请日：1956-11-23
Applicant: UPJOHN CO
Inventor： SEBEK OLDRICH K , SPERO GEORGE B
CPC classification number: C07J5/00 , C07J75/00 , Y10S435/843 , Y10S435/911 , Y10S435/929
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