公开(公告)号：US10517962B2

公开(公告)日：2019-12-31

申请号：US14394004

申请日：2013-04-12

申请人： Universite Claude Bernard Lyon I ,  Nano-H ,  Centre National de la Recherche Scientifique—CNRS ,  Universite Joseph Fourier

发明人： Yannick Cremillieux ,  Andrea Bianchi ,  Sandrine Dufort ,  Jean-Luc Coll ,  Francois Lux ,  Olivier Tillement

IPC分类号： A61K47/69 ,  A61K49/00 ,  A61K41/00 ,  A61K49/10 ,  A61K49/18 ,  A61K51/12 ,  A61K9/51 ,  A61K49/04

摘要： The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.

公开(公告)号：US11529316B2

公开(公告)日：2022-12-20

申请号：US16705305

申请日：2019-12-06

申请人： Universite Claude Bernard Lyon I ,  Nano-H ,  Centre National de la Recherche Scientifique—CNRS ,  Universite Grenoble Alpes ,  Universite de Bordeaux

发明人： Yannick Cremillieux ,  Andrea Bianchi ,  Sandrine Dufort ,  Jean-Luc Coll ,  Francois Lux ,  Olivier Tillement

IPC分类号： A61K9/51 ,  A61K49/10 ,  A61K49/00 ,  A61K49/18 ,  A61K51/12 ,  A61K49/04 ,  A61K47/69 ,  A61K41/00

摘要： The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.

公开(公告)号：US20150050217A1

公开(公告)日：2015-02-19

申请号：US14394004

申请日：2013-04-12

申请人： Universite Claude Bernard Lyon 1 ,  Nano-H ,  Centre National de la Recherche Scientifique-CNRS ,  Universite Joseph Fourier

发明人： Yannick Cremillieux ,  Andrea Bianchi ,  Sandrine Dufort ,  Jean-Luc Coll ,  Francois Lux ,  Olivier Tillement

IPC分类号： A61K49/18 ,  A61K49/00 ,  A61K9/51 ,  A61K49/04 ,  A61K41/00 ,  A61K49/10

摘要： The invention relates to a novel use of ultrafine nanoparticles, of use as a diagnostic, therapeutic or theranostic agent, characterized by their mode of administration via the airways. The invention is also directed toward the applications which follow from this novel mode of administration, in particular for imaging the lungs, and the diagnosis or prognosis of pathological pulmonary conditions. In the therapeutic field, the applications envisioned are those of radiosensitizing or radioactive agents for radiotherapy (and optionally curietherapy), or for neutron therapy, or of agents for PDT (photodynamic therapy), in particular for the treatment of lung tumors.

摘要翻译： 本发明涉及超细纳米颗粒的新用途，其用作诊断，治疗或治疗剂，其特征在于其经由气道的给药模式。 本发明还涉及从这种新型施用模式，特别是用于对肺成像，以及病理性肺病的诊断或预后的应用。 在治疗领域中，设想的应用是用于放射增敏剂或放射剂（用于放射疗法）或用于中子治疗或PDT（光动力疗法）的药剂，特别是用于治疗肺肿瘤的应用。