专利检索 ap:("University of Florida Research Foundation, Inc.") AND inv:"Eric C. Bartee" 第 1 页

1.

发明申请
Methods for Treating or Preventing Graft Versus Host Disease 审中-公开

公开(公告)号：US20180064760A1

公开(公告)日：2018-03-08

申请号：US15676438

申请日：2017-08-14

申请人： University of Florida Research Foundation, Inc.

发明人： Douglas G. McFadden , Eric C. Bartee , Christopher R. Cogle

IPC分类号： A61K35/28 , C12N5/0783 , A61K35/14 , A61K35/12

CPC分类号： A61K35/28 , A61K35/14 , A61K35/17 , A61K35/768 , A61K2035/122 , A61K2035/124 , C12N5/0636 , C12N2710/24041

摘要： A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat or prevent GVHD in the host subject following infusion of the graft into the subject. After the contacting of the graft with the Myxoma Virus, the method comprises transplanting the virus-treated graft into the subject.

2.

发明授权
Myxoma-treated graft material for cancer treatment 有权

公开(公告)号：US10322149B2

公开(公告)日：2019-06-18

申请号：US15676438

申请日：2017-08-14

申请人： University of Florida Research Foundation, Inc.

发明人： Douglas G. McFadden , Eric C. Bartee , Christopher R. Cogle

IPC分类号： A61K35/28 , A61K35/768 , A61K35/17 , A61K35/14 , C12N5/0783 , A61K35/12

摘要： A method of treating or preventing graft versus host disease (GVHD) in a subject receiving a graft comprising hematopoietic cells is provided. The method comprises contacting the graft ex vivo with an amount of a Myxoma Virus effective to inhibit proliferation of T lymphocytes in the graft and to treat or prevent GVHD in the host subject following infusion of the graft into the subject. After the contacting of the graft with the Myxoma Virus, the method comprises transplanting the virus-treated graft into the subject.