公开(公告)号：US20180207318A1

公开(公告)日：2018-07-26

申请号：US15744942

申请日：2016-07-14

Applicant: University of Florida Research Foundation, Inc.

Inventor： CHRISTINE E. SCHMIDT ,  REBECCA ANN WACHS ,  ROBERT CHASE CORNELISON

IPC: A61L27/36 ,  C12N5/0793

CPC classification number: A61L27/3633 ,  A61K35/30 ,  A61K35/32 ,  A61K35/42 ,  A61L27/3687 ,  A61L27/54 ,  A61L2430/40 ,  C12N5/0619 ,  C12N2533/90

Abstract: Provided herein are methods of producing an acellular tissue product wherein the method can include the step of inducing apoptosis and washing the tissue after induction of apoptosis with a tonic solution. Also provided herein are acellular tissue products produced by the methods provided herein and methods of administering the acellular tissue products to a subject in need thereof.