公开(公告)号：US20180284092A1

公开(公告)日：2018-10-04

申请号：US15863463

申请日：2018-01-05

申请人： University of Florida Research Foundation, Inc.

发明人： Zhaohui Tong ,  Suguna Jairam

IPC分类号： G01N33/02 ,  G01N21/78 ,  C08G83/00 ,  B82Y30/00 ,  B82Y40/00 ,  B65D77/24 ,  B65D81/34 ,  C09B67/02

摘要： Nanoparticles and compositions thereof are provided for detecting and/or preventing food spoilage. Methods of making the nanoparticles and compositions, and methods of using the nanoparticles and compositions, e.g. in food packaging, are also provided. The nanoparticles can have a hydrophobic core containing a hydrophobic active agent, e.g. a hydrophobic dye and/or an antimicrobial agent, for detecting and/or preventing food spoilage. The nanoparticles can also have a copolymer of a hydrophobic polymer repeat unit, e.g. styrene or lactic acid, and a pH responsive dendrimer repeat unit. The pH responsive dendrimer repeat unit can have a pH responsive amine core having a plurality of branched acrylate arms extending therefrom. The nanoparticles can be chemically stable at neutral pH, and then release the hydrophobic active agent at a pH range indicative of food spoilage. By releasing the hydrophobic dye and/or antimicrobial agent, the nanoparticles can detect and/or inhibit food spoilage.

公开(公告)号：US11435333B2

公开(公告)日：2022-09-06

申请号：US15863463

申请日：2018-01-05

申请人： University of Florida Research Foundation, Inc.

发明人： Zhaohui Tong ,  Suguna Jairam

IPC分类号： G01N33/02 ,  G01N21/78 ,  C08G83/00 ,  B82Y30/00 ,  B82Y40/00 ,  B65D77/24 ,  B65D81/34 ,  C09B67/02 ,  B01J13/18 ,  C09B67/46 ,  C09B67/08 ,  G01N33/12

摘要： Nanoparticles and compositions thereof are provided for detecting and/or preventing food spoilage. Methods of making the nanoparticles and compositions, and methods of using the nanoparticles and compositions, e.g. in food packaging, are also provided. The nanoparticles can have a hydrophobic core containing a hydrophobic active agent, e.g. a hydrophobic dye and/or an antimicrobial agent, for detecting and/or preventing food spoilage. The nanoparticles can also have a copolymer of a hydrophobic polymer repeat unit, e.g. styrene or lactic acid, and a pH responsive dendrimer repeat unit. The pH responsive dendrimer repeat unit can have a pH responsive amine core having a plurality of branched acrylate arms extending therefrom. The nanoparticles can be chemically stable at neutral pH, and then release the hydrophobic active agent at a pH range indicative of food spoilage. By releasing the hydrophobic dye and/or antimicrobial agent, the nanoparticles can detect and/or inhibit food spoilage.