专利检索 ap:("University of Maryland, Baltimore") AND inv:"Paul S. Shapiro" 第 1 页

1.

发明授权
Non-ATP/catalytic site p38 mitogen activated protein kinase inhibitors 有权

公开(公告)号：US11078171B2

公开(公告)日：2021-08-03

申请号：US16872114

申请日：2020-05-11

申请人： University of Maryland, Baltimore

发明人： Paul S. Shapiro , Alexander D. Mackerell, Jr. , Jeffrey D. Hasday , Steven Fletcher

IPC分类号： C07D295/03

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

2.

发明授权
Non-catalytic substrate-selective p38alpha-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof 有权

公开(公告)号：US11911393B2

公开(公告)日：2024-02-27

申请号：US18169785

申请日：2023-02-15

申请人： University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs

发明人： Paul S. Shapiro , Alexander D. Mackerell, Jr. , Jeffrey D. Hasday

IPC分类号： A61K31/5375 , A61K31/18 , A61K31/54 , A61P31/00 , A61P19/02 , A61P29/00 , A61P35/00

CPC分类号： A61K31/5375 , A61K31/18 , A61K31/54 , A61P19/02 , A61P29/00 , A61P31/00 , A61P35/00

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

3.

发明申请
NON-CATALYTIC SUBSTRATE-SELECTIVE P38alpha-SPECIFIC MAPK INHIBITORS WITH ENDOTHELIAL-STABILIZING AND ANTI-INFLAMMATORY ACTIVITY, AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20190151324A1

公开(公告)日：2019-05-23

申请号：US16312499

申请日：2017-06-22

申请人： University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs

发明人： Paul S. Shapiro , Alexander D. MacKerell, Jr. , Jeffrey D. Hasday

IPC分类号： A61K31/5375 , A61K31/54 , A61K31/18 , A61P29/00 , A61P35/00

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

4.

发明授权
Non-catalytic substrate-selective, p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof 有权

公开(公告)号：US11357781B2

公开(公告)日：2022-06-14

申请号：US17231598

申请日：2021-04-15

申请人： University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs

发明人： Paul S. Shapiro , Alexander D. MacKerell, Jr. , Jeffrey D. Hasday

IPC分类号： A61K31/5375 , A61K31/18 , A61K31/54 , A61P31/00 , A61P19/02 , A61P29/00 , A61P35/00

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

5.

发明授权
Non-catalytic substrate-selective p38α-specific MAPK inhibitors with endothelial-stabilizing and anti-inflammatory activity, and methods of use thereof 有权

公开(公告)号：US11911392B2

公开(公告)日：2024-02-27

申请号：US17740248

申请日：2022-05-09

申请人： University of Maryland, Baltimore , The United States of America as represented by the Department of Veterans Affairs

发明人： Paul S. Shapiro , Alexander D. Mackerell, Jr. , Jeffrey D. Hasday

IPC分类号： A61K31/5375 , A61K31/18 , A61K31/54 , A61P31/00 , A61P19/02 , A61P29/00 , A61P35/00

CPC分类号： A61K31/5375 , A61K31/18 , A61K31/54 , A61P19/02 , A61P29/00 , A61P31/00 , A61P35/00

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.

6.

发明授权
Non-ATP/catalytic site p38 Mitogen Activated Protein Kinase inhibitors 有权

公开(公告)号：US11718595B2

公开(公告)日：2023-08-08

申请号：US17349468

申请日：2021-06-16

申请人： University of Maryland, Baltimore

发明人： Paul S. Shapiro , Alexander D. Mackerell, Jr. , Jeffrey D. Hasday , Steven Fletcher

IPC分类号： C07D295/03

CPC分类号： C07D295/03

摘要： Compounds that inhibit p38α MAPK protein, and methods of using the same, are provided for treating or preventing diseases such as cancer or inflammatory diseases.