公开(公告)号：US20140234427A1

公开(公告)日：2014-08-21

申请号：US14349329

申请日：2012-10-05

Applicant: UNIVERSITY OF WARWICK

Inventor： Matthew Ian Gibson ,  Stefan Antonius Franciscus Bon

IPC: A01N1/02 ,  A01G1/00 ,  C07C7/20 ,  C09K8/52 ,  A61K47/32 ,  A23L3/375

CPC classification number: A01N1/0221 ,  A01G13/065 ,  A01G22/00 ,  A23B4/08 ,  A23B7/05 ,  A23L3/37 ,  A23L3/375 ,  A61K47/32 ,  B01J13/14 ,  C07C7/20 ,  C08F290/12 ,  C09K8/52 ,  C09K2208/22 ,  C08F212/08 ,  C08F212/36

Abstract: The invention provides a method of preventing or reducing the growth of crystals in a substance which is susceptible to crystal growth in which colloidal particles having an amphiphilic structure, e.g. Janus particles, are contacted with the substance. Colloidal particles suitable for use in the invention include cross-linked, colloidal materials formed from hydrophobic monomers such as acrylates or methacrylates and hydrophilic monomers such as those derived from acrylic and/or methacrylic acid. The colloidal particles find particular use in methods of cryopreservation of biological samples (e.g. cells, tissues or organs), as a texture modifier in frozen food products, in the inhibition of gas hydrate formation, and as scale inhibitors.

Abstract translation: 本发明提供一种防止或减少易于晶体生长的物质中的晶体的生长的方法，其中具有两亲性结构的胶体颗粒，例如， Janus颗粒与物质接触。 适用于本发明的胶体颗粒包括由疏水单体如丙烯酸酯或甲基丙烯酸酯形成的交联的胶体材料和亲水性单体，例如衍生自丙烯酸和/或甲基丙烯酸的那些。 胶体颗粒特别用于生物样品（例如细胞，组织或器官）的冷冻保存，冷冻食品中的纹理调节剂，抑制气体水合物形成和作为阻垢剂的方法中。

公开(公告)号：US20210387187A1

公开(公告)日：2021-12-16

申请号：US17330986

申请日：2021-05-26

Applicant: University of Warwick

Inventor： Matthew Ian Gibson ,  Sarah-Jane RICHARDS ,  Alexander Neil BAKER

IPC: B01L3/00 ,  G01N33/543 ,  G01N33/58 ,  G01N33/569

Abstract: The present invention relates to methods for the detection of an analyte, such as coronavirus (e.g. SARS-CoV-2) or other virus particles and proteins, in a test sample. The invention also provides a flow device for use in such methods. Additionally, there is provided a coronavirus-binding reagent having the structure [sialic acid]-[linker]-[polymer]-[gold nanoparticle] for use in the devices and methods of the invention.