METHOD AND APPARATUS FOR FLOW-BASED, SINGLE-PARTICLE AND/OR SINGLE-MOLECULE ANALYSIS

    公开(公告)号:US20240027325A1

    公开(公告)日:2024-01-25

    申请号:US18250613

    申请日:2021-11-10

    CPC classification number: G01N15/1434 G01N2015/0065

    Abstract: Systems and methods for analyzing particles flowing in a channel are described. In an embodiment, the channel is configured to flow a particle through a lumen of the channel, the channel defining an interrogation window configured to allow light to pass into and out of the lumen; a light engine comprising: a first light source positioned to output first excitation light onto a first portion of the channel in the interrogation window; and a second light source positioned to output second excitation light onto a second portion of the channel in the interrogation window separate from the first portion. In an embodiment, the systems include an emission fiber bundle comprising a first emission optical fiber and a second emission optical fiber, wherein a proximal end of first emission optical fiber and second emission optical fiber are arranged in an emission fiber bundle head.

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