公开(公告)号：US20210187071A1

公开(公告)日：2021-06-24

申请号：US16754799

申请日：2018-10-26

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Paul B. FISHER ,  Anjan K. PRADHAN ,  Swadesh K. DAS ,  Luni EMDAD

IPC: A61K38/20 ,  A61K31/122 ,  A61K31/5377 ,  A61P35/04

Abstract: In various aspects, the present disclosure provides methods of preventing metastasis to bone in a subject with cancer, as well as compositions and kits for use in the same. In various aspects, the present disclosure provides methods of treating bone metastasis in a subject with cancer, as well as compositions and kits for use in the same. In embodiments, compositions comprise an MDA-7/IL-24 protein.