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公开(公告)号：US20170087363A1
公开(公告)日：2017-03-30
申请号：US15247010
申请日：2016-08-25
Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
Inventor： Richard M. Costanzo , Woon-Hong Yeo
Abstract: The system includes various embodiments of components, including (1) a sensor array, (2) a processor, (3) a transmitter, (4) a receiver-stimulator, and (5) an implantable electrode array. The gustatory implant system generates tastant fingerprints by detecting tastants with an array of chemical sensors and then transmitting variable spatiotemporal stimulation patterns for an electrode array with electrode stimulating points positioned at different locations in the gustatory cortex (e.g., stimulating the chorda tympanic nerve). Different patterns of activity in the gustatory cortex are thereby generated which mimic the sense of taste in a subject. Once trained the system should be usable by a subject to detect or correctly identify or perceive one or more tastes. The system may also include an external electronic device for processing and displaying information to monitor ingestion of various substances in a subject.
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公开(公告)号：US09517342B2
公开(公告)日：2016-12-13
申请号：US14783450
申请日：2014-03-12
Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
Inventor： Richard M. Costanzo , Daniel Coelho
CPC classification number: A61N1/3606 , A61N1/0531 , A61N1/0546 , A61N1/3601 , A61N1/36128 , A61N1/36153 , A61N1/36167 , A61N1/37211
Abstract: The system includes five components: (1) a sensor array, (2) a processor, (3) a transmitter, (4) a receiver-stimulator, and (5) an implantable electrode array. The olfactory implant system generates odor fingerprints by detecting odors with an array of chemical sensors and then transmitting variable spatio-temporal stimulation patterns for an electrode array with electrode stimulating points positioned at different locations in the olfactory cortex (e.g., stimulating the olfactory bulb). Different patterns of activity in the olfactory cortex are thereby generated which mimic the sense of smell in a subject. Once trained the system should be usable by a subject to detect or correctly identify one or more odors.
Abstract translation: 该系统包括五个部件：（1）传感器阵列，（2）处理器，（3）发射器，（4）接收器 - 刺激器，和（5）可植入电极阵列。 嗅觉植入系统通过用化学传感器阵列检测气味产生气味指纹，然后用位于嗅觉皮层中不同位置的电极刺激点（例如刺激嗅球）的电极阵列传输可变时空刺激图案。 由此产生嗅觉皮质中不同的活动模式，模仿受试者的嗅觉。 一旦被训练，系统应该被主体使用以检测或正确识别一种或多种气味。
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公开(公告)号：US10702695B2
公开(公告)日：2020-07-07
申请号：US15247010
申请日：2016-08-25
Applicant: VIRGINIA COMMONWEALTH UNIVERSITY
Inventor： Richard M. Costanzo , Woon-Hong Yeo
Abstract: The system includes various embodiments of components, including (1) a sensor array, (2) a processor, (3) a transmitter, (4) a receiver-stimulator, and (5) an implantable electrode array. The gustatory implant system generates tastant fingerprints by detecting tastants with an array of chemical sensors and then transmitting variable spatiotemporal stimulation patterns for an electrode array with electrode stimulating points positioned at different locations in the gustatory cortex (e.g., stimulating the chorda tympanic nerve). Different patterns of activity in the gustatory cortex are thereby generated which mimic the sense of taste in a subject. Once trained the system should be usable by a subject to detect or correctly identify or perceive one or more tastes. The system may also include an external electronic device for processing and displaying information to monitor ingestion of various substances in a subject.
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