公开(公告)号：US10052097B2

公开(公告)日：2018-08-21

申请号：US14307073

申请日：2014-06-17

申请人： Adi Mashiach ,  Itzik Mashiach ,  Guy Siman

发明人： Adi Mashiach ,  Itzik Mashiach ,  Guy Siman

IPC分类号： A61B17/04 ,  A61B5/04 ,  A61B5/0488 ,  A61N1/378 ,  A61N1/05 ,  A61N1/36 ,  A61N1/372 ,  A61B17/30 ,  H04B5/00

CPC分类号： A61B17/0491 ,  A61B5/04001 ,  A61B5/0488 ,  A61B17/0482 ,  A61B17/30 ,  A61N1/0526 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/36071 ,  A61N1/3611 ,  A61N1/36125 ,  A61N1/36189 ,  A61N1/37229 ,  A61N1/3787 ,  H04B5/0031 ,  H04B5/0037 ,  H04B5/0043 ,  H04B5/0081 ,  H04B5/0093

摘要： An implant unit delivery tool is provided. The implant delivery tool may include a body, a holder disposed at a distal end of the body and adapted to hold an implant unit, and an implant activator associated with the body, the implant activator configured to receive power from a power source. The implant activator may be configured to selectively and wirelessly transfer power from the power source to the implant unit during implantation of the implant unit into the body of a subject to cause modulation of at least one nerve in the body of the subject, and determine a degree of nerve modulation response resulting from the selective and wireless transfer of power from the power source to the implant unit claims.

公开(公告)号：US20180229044A1

公开(公告)日：2018-08-16

申请号：US15816105

申请日：2017-11-17

申请人： The Board of Trustees of the Leland Stanford Junior University

发明人： Ada Shuk Yan Poon ,  Alexander Yeh ,  Yuji Tanabe ,  John Ho ,  Sanghoek Kim

IPC分类号： A61N1/378 ,  A61H1/00 ,  H02J7/02 ,  A61B5/0215 ,  A61N7/00 ,  A61N1/05 ,  A61N1/362 ,  A61B5/00 ,  A61M5/142 ,  A61B5/145 ,  A61N1/375 ,  A61N5/06 ,  A61N1/36 ,  A61B5/04 ,  A61M31/00 ,  A61N1/372 ,  A61B5/026 ,  A61H23/00 ,  H02J50/10 ,  A61B5/01 ,  A61N1/365 ,  H01Q9/04 ,  H01Q1/27

CPC分类号： A61N1/3787 ,  A61B5/0008 ,  A61B5/0013 ,  A61B5/0031 ,  A61B5/0084 ,  A61B5/01 ,  A61B5/0215 ,  A61B5/026 ,  A61B5/04 ,  A61B5/14503 ,  A61B5/14539 ,  A61B5/14542 ,  A61B5/686 ,  A61B2560/0219 ,  A61H1/008 ,  A61H23/004 ,  A61H2201/1207 ,  A61M5/14276 ,  A61M31/002 ,  A61M2205/8206 ,  A61N1/0534 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/3601 ,  A61N1/3605 ,  A61N1/36125 ,  A61N1/36139 ,  A61N1/362 ,  A61N1/365 ,  A61N1/37211 ,  A61N1/37229 ,  A61N1/3756 ,  A61N5/0601 ,  A61N7/00 ,  H01Q1/273 ,  H01Q9/0407 ,  H02J7/025 ,  H02J50/10 ,  H02J50/20 ,  H02J50/23

摘要： Implantable devices and/or sensors can be wirelessly powered by controlling and propagating electromagnetic waves in a patient's tissue. Such implantable devices/sensors can be implanted at target locations in a patient, to stimulate areas such as the heart, brain, spinal cord, or muscle tissue, and/or to sense biological, physiological, chemical attributes of the blood, tissue, and other patient parameters. The propagating electromagnetic waves can be generated with sub-wavelength structures configured to manipulate evanescent fields outside of tissue to generate the propagating waves inside the tissue. Methods of use are also described.

公开(公告)号：US20180207431A1

公开(公告)日：2018-07-26

申请号：US15897107

申请日：2018-02-14

申请人： Adi MASHIACH ,  Tim RUYTJENS ,  Itzik MASHIACH

发明人： Adi MASHIACH ,  Tim RUYTJENS ,  Itzik MASHIACH

IPC分类号： A61N1/378 ,  A61N1/36

CPC分类号： A61N1/3787 ,  A61N1/0526 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/36125 ,  A61N1/37229 ,  H02J50/12 ,  H04B5/0031 ,  H04B5/0037 ,  H04B5/0081 ,  H04B5/0093

摘要： Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to he received by and retained by a receiver associated with a housing configured for mounting on the carrier.

公开(公告)号：US20180126162A1

公开(公告)日：2018-05-10

申请号：US15718097

申请日：2017-09-28

申请人： MED-EL ELEKTROMEDIZINISCHE GERAETE GMBH

发明人： Michael J. Pitman

IPC分类号： A61N1/36

CPC分类号： A61N1/36067 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/36057 ,  A61N1/36164 ,  A61N1/36171 ,  A61N1/36175

摘要： A method and apparatus for using low levels of electrical stimulation to treat focal dystonia by stimulating the afferent nervous system and/or altering the function of the gamma motor neurons innervating muscles which experience symptomatic spasms.

公开(公告)号：US20180117334A1

公开(公告)日：2018-05-03

申请号：US15842956

申请日：2017-12-15

申请人： Ranu Jung

发明人： Ranu Jung

IPC分类号： A61N1/36 ,  A61N1/372

CPC分类号： A61N1/36139 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/37217

摘要： Adaptive systems and methods for automatically determining and continuously updating stimulation parameters for adjusting ventilation to accommodate a patient's specific physiology, metabolic needs, and muscle state are disclosed herein. Having a closed loop implementation, the system may comprise a controller including a neuromorphic controlled adaptive feed-forward Pattern Generator/Pattern Shaper (PG/PS) assembly, which controls respiratory muscle movement using electrical stimulation. This PG/PS assembly comprises a biomimetic design where the pattern generator includes a neural network mimicking the simplified connectivity pattern of respiratory related neurons in the brain stem to produce a rhythmic breathing pattern frequency and the pattern shaper includes a neural network mimicking the simplified connectivity pattern of neurons to produce a stimulus control signal. This biomimetic design for the controller automatically customizes and continually updates stimulation parameters to achieve a desired breathing pattern and, thereby, slow the development of muscle fatigue.

公开(公告)号：US20180117316A1

公开(公告)日：2018-05-03

申请号：US15562714

申请日：2016-03-16

申请人： INSPIRE MEDICAL SYSTEMS, INC.

发明人： Darrell Wagner ,  Quan Ni ,  John Rondoni ,  Dave Dieken

IPC分类号： A61N1/36 ,  A61B5/00 ,  A61B5/113 ,  A61B5/08

CPC分类号： A61N1/3601 ,  A61B5/0205 ,  A61B5/0816 ,  A61B5/0826 ,  A61B5/113 ,  A61B5/4818 ,  A61B5/4848 ,  A61B5/686 ,  A61N1/3611 ,  A61N1/36135 ,  A61N1/36146 ,  A61N1/36171 ,  G06F19/3481

摘要： A device for treating sleep disordered breathing includes a stimulation element to stimulate an airway-patency-related nerve.

公开(公告)号：US09950166B2

公开(公告)日：2018-04-24

申请号：US14307003

申请日：2014-06-17

申请人： NYXOAH SA

发明人： Adi Mashiach ,  Itzik Mashiach

IPC分类号： A61N1/05 ,  A61N1/36 ,  A61N1/375 ,  A61N1/378 ,  A61N2/00 ,  A61B5/11 ,  A61B5/113 ,  A61F5/56 ,  A61N1/372 ,  A61B5/08 ,  A61B5/00 ,  A61N2/02 ,  A61B5/0488

CPC分类号： A61N1/3611 ,  A61B5/0031 ,  A61B5/0488 ,  A61B5/08 ,  A61B5/11 ,  A61B5/113 ,  A61B5/4519 ,  A61B5/4818 ,  A61B5/682 ,  A61B5/6822 ,  A61B5/6833 ,  A61B5/6876 ,  A61B2560/0219 ,  A61B2562/164 ,  A61F5/566 ,  A61N1/0514 ,  A61N1/0526 ,  A61N1/0553 ,  A61N1/36003 ,  A61N1/3601 ,  A61N1/36057 ,  A61N1/3606 ,  A61N1/36075 ,  A61N1/36117 ,  A61N1/36135 ,  A61N1/36139 ,  A61N1/36146 ,  A61N1/37223 ,  A61N1/37229 ,  A61N1/3756 ,  A61N1/3787 ,  A61N2/006 ,  A61N2/02

摘要： An implant unit configured for implantation into a body of a subject is provided. The implant unit may include a flexible carrier unit including a central portion and two elongated arms extending from the central portion, an antenna, located on the central portion, configured to receive a signal, at least one pair of electrodes arranged on a first elongated arm of the two elongated arms. The at least one pair of electrodes may be adapted to modulate a first nerve. The elongated arms of the flexible carrier may be configured to form an open ended curvature around a muscle with the nerve to be stimulated within an arc of the curvature.

公开(公告)号：US20180078196A1

公开(公告)日：2018-03-22

申请号：US15825772

申请日：2017-11-29

申请人： Advanced Brain Monitoring, Inc.

发明人： Daniel J. Levendowski ,  Timothy Zavora ,  Philip R. Westbrook ,  Mirko Mitrovic ,  Bratislav Veljkovic ,  Chris Berka ,  Jonny Trejo

IPC分类号： A61B5/00 ,  A61M21/02 ,  A61B5/11 ,  A61B7/00 ,  A61B7/04 ,  A61F5/56 ,  A61B5/103 ,  A61M21/00 ,  A61N5/06 ,  A61B5/113 ,  A61N1/36

CPC分类号： A61B5/486 ,  A61B5/103 ,  A61B5/11 ,  A61B5/1116 ,  A61B5/113 ,  A61B5/4806 ,  A61B5/4809 ,  A61B5/4818 ,  A61B5/4833 ,  A61B5/6819 ,  A61B5/6822 ,  A61B5/6823 ,  A61B5/6831 ,  A61B5/7282 ,  A61B5/7405 ,  A61B7/003 ,  A61B7/04 ,  A61F5/56 ,  A61M21/02 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2021/0083 ,  A61M2205/3375 ,  A61M2205/3569 ,  A61M2205/3592 ,  A61M2205/502 ,  A61M2205/581 ,  A61M2205/583 ,  A61M2205/8206 ,  A61M2209/088 ,  A61M2230/63 ,  A61N1/3601 ,  A61N1/36014 ,  A61N2005/0653

摘要： Systems and methods for assessing compliance with position therapy. In an embodiment, position therapy is provided to a user while the user is wearing a position therapy device. The position therapy comprises, by the device, collecting positional data, determining positions of the user over a time period based on the positional data, and, when it is determined that the user is in a target position, providing feedback to the user to influence the user to change to a non-target position. In addition, the device stores a duration of use in its memory. The duration of use indicates a duration that the user has used the wearable position therapy device in each of one or more positions. An assessment of the user's compliance with the position therapy is then provided based, at least in part, on the duration of use.

公开(公告)号：US20180021586A9

公开(公告)日：2018-01-25

申请号：US13951754

申请日：2013-07-26

申请人： Adi Mashiach ,  Tim Ruytjens ,  Itzik Mashiach

发明人： Adi Mashiach ,  Tim Ruytjens ,  Itzik Mashiach

IPC分类号： A61N1/378 ,  A61N1/36

CPC分类号： A61N1/3787 ,  A61N1/0526 ,  A61N1/0558 ,  A61N1/3601 ,  A61N1/3611 ,  A61N1/36125 ,  A61N1/37229 ,  H02J50/12 ,  H04B5/0031 ,  H04B5/0037 ,  H04B5/0081 ,  H04B5/0093

摘要： Some embodiments of the present disclosure may include a device for conveying power from a location external to a subject to a location within the subject The device may include a flexible carrier, an adhesive on a first side of the carrier, a coil of electrically conductive material associated with the flexible carrier, and a mechanical connector extending from a second side of the carrier opposite the adhesive. The mechanical connector may be configured to be received by and retained by a receiver associated with a housing configured for mounting on the carrier.

公开(公告)号：US20180015281A1

公开(公告)日：2018-01-18

申请号：US15553223

申请日：2016-03-14

申请人： Case Western Reserve University

发明人： Kingman P. Strohl

IPC分类号： A61N1/36 ,  A61N1/05 ,  A61N1/04

CPC分类号： A61N1/3601 ,  A61B5/4818 ,  A61N1/0456 ,  A61N1/0492 ,  A61N1/0502 ,  A61N1/0517 ,  A61N1/36014 ,  A61N1/36057 ,  A61N1/3611

摘要： One aspect of the present disclosure relates to a system that provides an alternative to traditional treatments for sleep apnea. The system allows to apply an electrical stimulus through an electrode to stimulate an afferent nerve fiber while a patient is sleeping. The system also includes activating an endogenous central nervous system (CNS)-regulated reflex response to coordinate upper airway muscles based on the stimulation of the afferent nerve fiber. Based on the endogenous CNS-regulated reflex response, an airway patency in the sleeping patient can be regulated.