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公开(公告)号：US10849855B2
公开(公告)日：2020-12-01
申请号：US15854486
申请日：2017-12-26
申请人： VITREAN, INC.
IPC分类号： A61K9/14 , A61K9/00 , A61K9/08 , A61F9/007 , A61K31/43 , A61K31/7048 , A61F9/00 , A61K31/7036 , A61K47/38
摘要： A method of treating a detachment of a retina of an eye, the method including the steps of injecting a substance into a vitreous cavity of the eye, the substance slowing flow of fluid through the vitreous cavity into a subretinal space to reduce a rate of accumulation of a subretinal fluid in the subretinal space to below a rate of removal of the subretinal fluid from the subretinal space by retinal pigment epithelium; and permitting the retinal pigment epithelium to reattach the retina. The invention also includes devices for practicing the method.
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公开(公告)号：US20240358888A1
公开(公告)日：2024-10-31
申请号：US18553461
申请日：2022-03-31
申请人： Vitrean Inc.
CPC分类号： A61L27/20 , A61L27/52 , A61L27/54 , C08J3/075 , A61L2400/06 , C08J2305/08
摘要： Methods for mixing highly concentrated hydrogels are provided herein. The methods can be performed aseptically. Hydrogels created by this process may include many types of polymers, which may include glycosaminoglycans such as hyaluronic acid. The hydrogels formed by the methods described herein may further include and/or incorporate other molecules having biological activity.
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公开(公告)号：US20240316281A1
公开(公告)日：2024-09-26
申请号：US18554197
申请日：2022-03-31
申请人： Vitrean Inc.
CPC分类号： A61M5/31511 , A61K9/06 , A61K47/36 , A61M5/3286
摘要： A prefilled syringe containing a sterile ophthalmic pharmaceutical composition comprising an ultraconcentrated hydrogel and a pharmaceutically acceptable carrier, the prefilled syringe capable of storing the ultraconcentrated hydrogel and injecting the ultraconcentrated hydrogel with a reduced injection force into a biologic tissue.
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