公开(公告)号：US20220241605A1

公开(公告)日：2022-08-04

申请号：US17577887

申请日：2022-01-18

Applicant: Virginia Commonwealth University

Inventor： Ivan C. Carmona Tortolero ,  Ravi L. Hadimani ,  Mark S. Baron ,  Deepak Kumbhare

IPC: A61N2/02 ,  A61N2/00

Abstract: An example method includes positioning above the transcranial region, an arrangement of solenoids, and selecting a target zone from among a plurality of zones. A zone-specific set of Q solenoids is identified from the arrangement of solenoids, based on the target zone. The zone-specific set includes a pair of mutually adjacent ones of the solenoids. A Q-element solenoid feed modulation state vector is generated, which defines a Q-current element feed current modulation state. The Q-current element feed current modulation state is configured to cause the zone-specific set of Q solenoids to generate Q individual, spatially configured, time-varying magnetic fields that, in combination, establish a transcranial magnetic stimulation (TMS) inducing time-varying magnetic field, which induces a target hotspot TMS electric field. The hotspot TMS electric field is focalized to the target zone.

公开(公告)号：US10575726B2

公开(公告)日：2020-03-03

申请号：US14774152

申请日：2014-03-12

Applicant: VIRGINIA COMMONWEALTH UNIVERSITY

Inventor： Paul A. Wetzel ,  Mark S. Baron ,  George T. Gitchel

IPC: A61B3/113 ,  A61B5/00 ,  A61B5/11

Abstract: Objects of interest which project beyond the fovea are poorly resolved and lack color information, requiring movement of the eyes in order to obtain a comprehensive image and perception of the surrounding world. Eye movements emanate from different areas of the brain which can be affected by disease and or injury. As such, different neurological disorders will affect a myriad of eye movements in a variety of different ways. An automated system and method, capable of detecting, analyzing and summarizing a person's eye movements is used to detect (diagnose) (either before or after symptoms of said neurological disease are apparent), confirm a prior diagnosis, and/or to monitor the treatment effectiveness for a variety of neurological diseases, neurological movement disorders and potential brain injuries. The analyzed and summarized eye movements are cataloged, interpreted and utilized in a diagnostic matrix in order to highlight and distinguish abnormal eye movements, and to provide an objective clinical or pre-clinical/pre-symptomatic diagnosis based on the non-invasive testing procedures.