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公开(公告)号:US20230227477A1
公开(公告)日:2023-07-20
申请号:US18002535
申请日:2021-06-24
Applicant: WAKE FOREST UNIVERSITY HEALTH SCIENCES
Inventor: John C. Lukesh, III , Katherine Virginia Ambrose
IPC: C07F5/02
CPC classification number: C07F5/02
Abstract: Provided herein according to some embodiments of the invention are aryl boronate and/or aryl diaminoboryl compounds. Also provided are methods of detecting the presence of hydrogen peroxide (H2O2) and/or other reactive oxygen species (ROS) in a cell and/or tissue by contacting the cell and/or tissue with aryl boronate and/or aryl diaminoboryl compounds. Also provided according to embodiments of the invention are methods of producing persulfides in the presence of hydrogen peroxide (H2O2) and/or other reactive oxygen species (ROS) in a cell and/or tissue by contacting the cell and/or tissue with aryl boronate and/or aryl diaminoboryl compounds.