公开(公告)号：US11779464B2

公开(公告)日：2023-10-10

申请号：US16618926

申请日：2018-06-12

Applicant: WAKE FOREST UNIVERSITY HEALTH SCIENCES

Inventor： Phillip Kim ,  Anthony Atala ,  David James Mccoul

IPC: A61F2/24 ,  A61B34/10 ,  G16H50/50 ,  G16H30/40 ,  G06F30/20 ,  B33Y50/02 ,  B33Y80/00

CPC classification number: A61F2/2481 ,  A61B34/10 ,  G06F30/20 ,  G16H30/40 ,  G16H50/50 ,  A61B2034/102 ,  A61B2034/105 ,  A61B2034/108 ,  A61F2240/002 ,  A61F2250/0097 ,  B33Y50/02 ,  B33Y80/00

Abstract: Provided herein is a method of forming a ventricular support device for a diseased heart, including providing imaging data of the diseased heart, forming a three-dimensional (3D) heart model based on the imaging data, providing strain data including a plurality of strain estimates for at least one segment of the diseased heart, mapping the plurality of strain estimates onto corresponding portions of the 3D heart model to form a 3D diseased heart model, based on the 3D diseased heart model, forming a model of the ventricular support device configured to surround at least a portion of the diseased heart and provide support based upon said strain estimates, and converting the model of the ventricular support device to a digital file useful for directing a 3D printer device to print said ventricular support device for said diseased heart. Also provided is a customized ventricular support device so produced.

公开(公告)号：US20200085579A1

公开(公告)日：2020-03-19

申请号：US16618926

申请日：2018-06-12

Applicant: WAKE FOREST UNIVERSITY HEALTH SCIENCES

Inventor： Phillip Kim ,  Anthony Atala ,  David James Mccoul

IPC: A61F2/24 ,  G16H50/50 ,  G16H30/40 ,  A61B34/10

Abstract: Provided herein is a method of forming a ventricular support device for a diseased heart, including providing imaging data of the diseased heart, forming a three-dimensional (3D) heart model based on the imaging data, providing strain data including a plurality of strain estimates for at least one segment of the diseased heart, mapping the plurality of strain estimates onto corresponding portions of the 3D heart model to form a 3D diseased heart model, based on the 3D diseased heart model, forming a model of the ventricular support device configured to surround at least a portion of the diseased heart and provide support based upon said strain estimates, and converting the model of the ventricular support device to a digital file useful for directing a 3D printer device to print said ventricular support device for said diseased heart. Also provided is a customized ventricular support device so produced.