公开(公告)号：US11608355B2

公开(公告)日：2023-03-21

申请号：US16648146

申请日：2018-09-17

Applicant: WAVE LIFE SCIENCES LTD.

Inventor： Keith Andrew Bowman ,  Chandra Vargeese ,  David Charles Donnell Butler ,  Pachamuthu Kandasamy ,  Mohammed Rowshon Alam ,  Mamoru Shimizu ,  Stephany Michelle Standley ,  Vincent Aduda ,  Gopal Reddy Bommineni ,  Snehlata Tripathi ,  Ilia Korboukh

IPC: C07H21/02 ,  C07H21/04

Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.

公开(公告)号：US20230348524A1

公开(公告)日：2023-11-02

申请号：US18185901

申请日：2023-03-17

Applicant: WAVE LIFE SCIENCES LTD.

Inventor： Keith Andrew Bowman ,  Chandra Vargeese ,  David Charles Donnell Butler ,  Pachamuthu Kandasamy ,  Mohammed Rowshon Alam ,  Mamoru Shimizu ,  Stephany Michelle Standley ,  Vincent Aduda ,  Gopal Reddy Bommineni ,  Snehlata Tripathi ,  Ilia Korboukh

IPC: C07H21/02 ,  C07H21/04

CPC classification number: C07H21/02 ,  C07H21/04

Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.

公开(公告)号：US20200231620A1

公开(公告)日：2020-07-23

申请号：US16648146

申请日：2018-09-17

Applicant: Keith Andrew BOWMAN ,  Chandra VARGEESE ,  David Charles Donnell BUTLER ,  Pachamuthu KANDASAMY ,  Mohammed Rowshon ALAM ,  Mamoru SHIMIZU ,  Stephany Michelle STANDLEY ,  Vincent ADUDA ,  Gopal Reddy BOMMINENI ,  Snehlata TRIPATHI ,  Ilia KORBOUKH ,  WAVE LIFE SCIENCES LTD.

Inventor： Keith Andrew Bowman ,  Chandra Vargeese ,  David Charles Donnell Butler ,  Pachamuthu Kandasamy ,  Mohammed Rowshon Alam ,  Mamoru Shimizu ,  Stephany Michelle Standley ,  Vincent Aduda ,  Gopal Reddy Bommineni ,  Snehlata Tripathi ,  Ilia Korboukh

IPC: C07H21/02 ,  C07H21/04

Abstract: Among other things, the present disclosure provides technologies for oligonucleotide preparation, particularly chirally controlled oligonucleotide preparation, which technologies provide greatly improved crude purity and yield, and significantly reduce manufacturing costs.