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公开(公告)号：US20210072252A1
公开(公告)日：2021-03-11
申请号：US17088898
申请日：2020-11-04
发明人： James J. Havranek , Benjamin Borgo
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
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2.发明授权公开(公告)号：US09435810B2
公开(公告)日：2016-09-06
申请号：US14211448
申请日：2014-03-14
发明人： James J. Havranek , Benjamin Borgo
CPC分类号： G01N33/6824 , C12N9/485 , C12N9/50 , C12N9/641 , C12N9/93 , C12Y304/11018 , C12Y601/0101 , C12Y601/0102 , C12Y601/01021
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
摘要翻译： 提供了蛋白质或肽数字分析的试剂和方法。 本文具体提供的是用于鉴定多肽的N-末端氨基酸或N-末端磷酸化氨基酸的蛋白质。 另外，描述了用于Edman降解反应的切割步骤的酶和使用该酶的方法。
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公开(公告)号：US10017832B2
公开(公告)日：2018-07-10
申请号：US15247452
申请日：2016-08-25
发明人： James J. Havranek , Chi Zhang , Joseph C. Corbo , Connie A. Myers , Robi D. Mitra , Zongtai Qi
CPC分类号： C12Y207/07 , C12N9/1241 , C12N15/85 , C12N2800/30
摘要： The present invention relates to enzymes, compositions and methods for catalyzing site specific recombination at asymmetric sites.
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4.发明申请公开(公告)号：US20170058297A1
公开(公告)日：2017-03-02
申请号：US15247452
申请日：2016-08-25
发明人： James J. Havranek , Chi Zhang , Joseph C. Corbo , Connie A. Myers , Robi D. Mitra , Zongtai Qi
CPC分类号： C12Y207/07 , C12N9/1241 , C12N15/85 , C12N2800/30
摘要： The present invention relates to enzymes, compositions and methods for catalyzing site specific recombination at asymmetric sites.
摘要翻译： 本发明涉及在不对称位点催化位点特异性重组的酶，组合物和方法。
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5.发明申请公开(公告)号：US20170052194A1
公开(公告)日：2017-02-23
申请号：US15255433
申请日：2016-09-02
发明人： James J. Havranek , Benjamin Borgo
CPC分类号： G01N33/6824 , C12N9/485 , C12N9/50 , C12N9/52 , C12N9/641 , C12N9/93 , C12Y304/11018 , C12Y601/0101 , C12Y601/0102 , C12Y601/01021
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
摘要翻译： 提供了蛋白质或肽数字分析的试剂和方法。 本文具体提供的是用于鉴定多肽的N-末端氨基酸或N-末端磷酸化氨基酸的蛋白质。 另外，描述了用于Edman降解反应的切割步骤的酶和使用该酶的方法。
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公开(公告)号：US20240201199A1
公开(公告)日：2024-06-20
申请号：US18524884
申请日：2023-11-30
发明人： James J. Havranek , Benjamin Borgo
CPC分类号： G01N33/6824 , C12N9/485 , C12N9/52 , C12N9/641 , C12N9/93 , C12Y304/11018 , C12Y601/0101 , C12Y601/0102 , C12Y601/01021
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
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公开(公告)号：US10852305B2
公开(公告)日：2020-12-01
申请号：US16907813
申请日：2020-06-22
发明人： James J. Havranek , Benjamin Borgo
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
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公开(公告)号：US20200319200A1
公开(公告)日：2020-10-08
申请号：US16907813
申请日：2020-06-22
发明人： James J. Havranek , Benjamin Borgo
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
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9.发明申请公开(公告)号：US20140273004A1
公开(公告)日：2014-09-18
申请号：US14211448
申请日：2014-03-14
发明人： James J. Havranek , Benjamin Borgo
CPC分类号： G01N33/6824 , C12N9/485 , C12N9/50 , C12N9/641 , C12N9/93 , C12Y304/11018 , C12Y601/0101 , C12Y601/0102 , C12Y601/01021
摘要： Reagents and methods for the digital analysis of proteins or peptides are provided. Specifically provided herein are proteins for identifying the N-terminal amino acid or N-terminal phosphorylated amino acid of a polypeptide. Also, an enzyme for use in the cleavage step of the Edman degradation reaction and a method for using this enzyme are described.
摘要翻译： 提供了蛋白质或肽数字分析的试剂和方法。 本文具体提供的是用于鉴定多肽的N-末端氨基酸或N-末端磷酸化氨基酸的蛋白质。 另外，描述了用于Edman降解反应的切割步骤的酶和使用该酶的方法。
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