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公开(公告)号：US20210085618A1
公开(公告)日：2021-03-25
申请号：US16955336
申请日：2018-12-21
发明人： Gautam BEHL , Sangeeta KUMARI , Niall O'REILLY , Orla O'DONOVAN , Peter MCLOUGHLIN , David KENT , Laurence FITZHENRY , Elke BEHAEGHEL
IPC分类号： A61K9/51 , A61K9/00 , A61K31/573 , A61F9/00
摘要： This invention relates to a Nanostructured Lipid Carrier (NLC) particle comprising a therapeutic agent encapsulated therein for ocular delivery of the therapeutic agent, wherein the Nanostructured Lipid Carrier comprises: (i) a solid outer shell comprising a solid lipid, and (ii) a liquid core comprising a liquid lipid; and wherein the core comprises the therapeutic agent. Compositions of the NLC particles, use of the NLC particles, methods of treatment or prevention of an eye disorder and an eye drop dispenser are also provided.
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公开(公告)号：US20240207195A1
公开(公告)日：2024-06-27
申请号：US18458828
申请日：2023-08-30
发明人： Gautam BEHL , Sangeeta KUMARI , Niall O'REILLY , Orla O'DONOVAN , Peter MCLOUGHLIN , David KENT , Laurence FITZHENRY , Elke BEHAEGHEL
CPC分类号： A61K9/5123 , A61F9/0026 , A61K9/0048 , A61K31/573 , A61K45/06 , B82Y5/00
摘要： This invention relates to a Nanostructured Lipid Carrier (NLC) particle comprising a therapeutic agent encapsulated therein for ocular delivery of the therapeutic agent, wherein the Nanostructured Lipid Carrier comprises: (i) a solid outer shell comprising a solid lipid, and (ii) a liquid core comprising a liquid lipid; and wherein the core comprises the therapeutic agent. Compositions of the NLC particles, use of the NLC particles, methods of treatment or prevention of an eye disorder and an eye drop dispenser are also provided.
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