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    2-(3-Iodo-2-propynyloxy)-ethyl carbamates, the preparation thereof, and their use as antimicrobial agents
    2.
    发明授权
    2-(3-Iodo-2-propynyloxy)-ethyl carbamates, the preparation thereof, and their use as antimicrobial agents 失效
    2-（3-碘-2-丙炔氧基） - 乙基氨基甲酸酯，其制备及其作为抗微生物剂的用途

    公开(公告)号：US4474807A

    公开(公告)日：1984-10-02

    申请号：US427881

    申请日：1982-09-29

    申请人： Werner Gerhardt ,  Rudolf Lehmann

    发明人： Werner Gerhardt ,  Rudolf Lehmann

    IPC分类号： A01N47/12 ,  A01N47/18 ,  A01N47/20 ,  A01N47/24 ,  C07C125/065

    CPC分类号： A01N47/24 ,  A01N47/12 ,  A01N47/18 ,  A01N47/20

    摘要： This invention is directed to novel antimicrobial agents. More particularly, this invention is directed to 2-(3-iodo-2-propynyloxy)-ethyl carbamates of the formula ##STR1## wherein R is hydrogen, linear or branched alkyl of from 1 to 12 carbon atoms, cycloalkyl of from 4 to 8 carbon atoms, aryl, substituted aryl, aralkyl, or arylsulfonyl;R.sup.1 and R.sup.2, which may be the same or different, each are hydrogen, linear or branched alkyl or alkenyl of from 1 to 6 carbon atoms, or cycloalkyl of from 5 to 7 carbon atoms, or R.sup.1 and R.sup.2, taken together, represent --(CH.sub.2).sub.m --, in which m is an integer of from 4 to 6; andR.sup.3, R.sup.4, R.sup.5, and R.sup.6, which may be the same or different, each represent hydrogen, alkyl of from 1 to 4 carbon atoms, or aryl, or CCl.sub.3, or R.sup.3 and R.sup.5 or R.sup.4 and R.sup.6, taken together, represent --(CH.sub.2).sub.n --, in which n is an integer of from 3 to 5,as well as a process for their preparation and their use as antimicrobial agents.

    摘要翻译： 本发明涉及新型抗微生物剂。 更具体地，本发明涉及式（I）的式（I）的2-（3-碘-2-丙炔氧基） - 乙基氨基甲酸酯，其中R是氢，具有1至12个碳原子的直链或支链烷基， 4至8个碳原子，芳基，取代的芳基，芳烷基或芳基磺酰基; R 1和R 2可以相同或不同，各自为氢，具有1至6个碳原子的直链或支链烷基或烯基或5至7个碳原子的环烷基，或者R 1和R 2一起表示 - （CH 2）m - ，其中m为4-6的整数; 和可以相同或不同的R 3，R 4，R 5和R 6各自表示氢，1至4个碳原子的烷基或芳基或CCl 3，或R 3和R 5或R 4和R 6一起表示 - （CH 2）n - ，其中n为3至5的整数，以及其制备方法及其作为抗微生物剂的用途。