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公开(公告)号:US20130231294A1
公开(公告)日:2013-09-05
申请号:US13623822
申请日:2012-09-20
申请人: William D Carlson , Peter C. Keck , Michael Sworin , Dattatreyamurty Bosukonda , Kellie Watson , Philippe Bey , Romesh Subramanian
发明人: William D Carlson , Peter C. Keck , Michael Sworin , Dattatreyamurty Bosukonda , Kellie Watson , Philippe Bey , Romesh Subramanian
IPC分类号: C07K7/08
CPC分类号: A61K38/10 , A61K9/0019 , A61K9/5021 , A61K9/5026 , A61K9/5031 , A61K9/5073 , A61K38/00 , A61K38/12 , C07K7/08 , C07K14/495 , G01N33/6872 , G01N2333/495
摘要: The present invention relates generally to tissue differentiation factor (TDF) analogs. More specifically, the invention relates to structure-based methods and compositions useful in designing, identifying, and producing molecules, which act as functional modulators of TDF-like receptors. The invention further relates to methods of detecting, preventing, and treating TDF-associated disorders.