Non-cytotoxic oriP replicon
    1.
    发明授权
    Non-cytotoxic oriP replicon 有权
    非细胞毒性oriP复制子

    公开(公告)号:US07465580B2

    公开(公告)日:2008-12-16

    申请号:US10848976

    申请日:2004-05-19

    摘要: The invention provides a vector encoding a derivative of EBNA-1 that is not cytotoxic when expressed efficiently in cells, which supports extrachromosomal replication, maintenance and transcription from extrachromosomal oriP containing vectors but does not substantially activate transcription from host cell genes. Also provided is a vector having oriP and encoding a derivative of EBNA-1. The vectors of the invention may be employed in vitro and in gene therapy.

    摘要翻译: 本发明提供编码EBNA-1衍生物的载体,当在细胞中有效表达时,其不具有细胞毒性,其支持来自染色体外含oriP的载体的染色体外复制,维持和转录,但基本上不激活宿主细胞基因的转录。 还提供了具有oriP并编码EBNA-1的衍生物的载体。 本发明的载体可以在体外和基因治疗中使用。

    METHOD AND APPARATUS FOR DOWNLOADING FILES
    2.
    发明申请
    METHOD AND APPARATUS FOR DOWNLOADING FILES 审中-公开
    下载文件的方法和装置

    公开(公告)号:US20120272274A1

    公开(公告)日:2012-10-25

    申请号:US13509689

    申请日:2010-09-10

    IPC分类号: H04N21/462

    摘要: A method and apparatus are provided for downloading a file which are applied in a mobile multimedia broadcast system. The method includes: a client displaying broadcast information to a user for the user selecting a file to be downloaded; the client receiving a selection of the user to the file to be downloaded, reading the broadcast information of the file to be downloaded which is selected by the user, and downloading the file to be downloaded locally when a broadcast start time included in the broadcast information of the file to be downloaded arrives. The method and apparatus can make a user complete the file downloading without manual intervention when using a mobile multimedia broadcast service, thereby saving a mass of manual operations of the user and improving service experience of the user.

    摘要翻译: 提供一种用于下载应用在移动多媒体广播系统中的文件的方法和装置。 该方法包括:客户端向用户显示广播信息以供用户选择要下载的文件; 客户端接收到要下载的文件的用户的选择,读取由用户选择的要下载的文件的广播信息,并且当包括在广播信息中的广播开始时间时下载本地下载的文件 要下载的文件到达。 该方法和装置可以在使用移动多媒体广播服务时使用户完成文件下载而无需手动干预,从而节省用户的大量手动操作并提高用户的服务体验。

    Non-cytotoxic oriP replicon
    3.
    发明申请
    Non-cytotoxic oriP replicon 有权
    非细胞毒性oriP复制子

    公开(公告)号:US20050260564A1

    公开(公告)日:2005-11-24

    申请号:US10848976

    申请日:2004-05-19

    摘要: The invention provides a vector encoding a derivative of EBNA-1 that is not cytotoxic when expressed efficiently in cells, which supports extrachromosomal replication, maintenance and transcription from extrachromosomal oriP containing vectors but does not substantially activate transcription from host cell genes. Also provided is a vector having oriP and encoding a derivative of EBNA-1. The vectors of the invention may be employed in vitro and in gene therapy.

    摘要翻译: 本发明提供了编码EBNA-1衍生物的载体,当在细胞中有效表达时,其不具有细胞毒性,其支持来自染色体外含oriP的载体的染色体外复制,维持和转录,但基本上不激活宿主细胞基因的转录。 还提供了具有oriP并编码EBNA-1的衍生物的载体。 本发明的载体可以在体外和基因治疗中使用。