公开(公告)号：US08038673B2

公开(公告)日：2011-10-18

申请号：US11472631

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08066701B2

公开(公告)日：2011-11-29

申请号：US11472923

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗卵圆孔卵泡（PFO）的方法和装置提供用导管装置向邻近PFO的组织施加能量，以基本上封闭PFO。 装置通常包括导管装置，其具有在其远端处或其近端处的至少一个能量传递构件，其被配置为向PFO组织施加能量以急剧，基本上关闭PFO。 施加的能量可以是单极性或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。 导管装置的一些实施例还包括靠近远端的一个或多个组织定位构件，用于帮助使PFO组织在一起，例如PFO覆盖构件，真空施加构件等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US07914527B2

公开(公告)日：2011-03-29

申请号：US11506230

申请日：2006-08-17

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US20120010608A1

公开(公告)日：2012-01-12

申请号：US13238659

申请日：2011-09-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/18 ,  A61B18/00

CPC分类号： A61B18/1492 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0644 ,  A61B17/083 ,  A61B17/10 ,  A61B18/1477 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/0061 ,  A61B2017/00615 ,  A61B2017/00623 ,  A61B2017/00668 ,  A61B2017/00867 ,  A61B2017/0641 ,  A61B2017/0645 ,  A61B2017/0649 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1425 ,  A61B2018/1472 ,  A61B2090/3614 ,  A61N7/022 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device fuirther include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗卵圆孔卵泡（PFO）的方法和装置提供用导管装置向邻近PFO的组织施加能量，以基本上封闭PFO。 装置通常包括导管装置，其具有在其远端处或其近端处的至少一个能量传递构件，其被配置为向PFO组织施加能量以急剧，基本上关闭PFO。 施加的能量可以是单极性或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。 导管装置的一些实施例还包括靠近远端的一个或多个组织定位构件，用于帮助使PFO组织在一起，例如PFO覆盖构件，真空施加构件等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US08075554B2

公开(公告)日：2011-12-13

申请号：US11472926

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08070747B2

公开(公告)日：2011-12-06

申请号：US11472924

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08038669B2

公开(公告)日：2011-10-18

申请号：US11249566

申请日：2005-10-12

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08038672B2

公开(公告)日：2011-10-18

申请号：US11472630

申请日：2006-06-21

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson S. Gifford, III ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B17/0057 ,  A61B17/0218 ,  A61B17/0644 ,  A61B17/083 ,  A61B17/10 ,  A61B18/1477 ,  A61B18/18 ,  A61B18/20 ,  A61B2017/00243 ,  A61B2017/00575 ,  A61B2017/00579 ,  A61B2017/00592 ,  A61B2017/00597 ,  A61B2017/0061 ,  A61B2017/00615 ,  A61B2017/00623 ,  A61B2017/00668 ,  A61B2017/00867 ,  A61B2017/0641 ,  A61B2017/0645 ,  A61B2017/0649 ,  A61B2018/00011 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/1425 ,  A61B2018/1472 ,  A61B2090/3614 ,  A61N7/022 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monopolar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

公开(公告)号：US08038671B2

公开(公告)日：2011-10-18

申请号：US11464755

申请日：2006-08-15

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B17/0057 ,  A61B17/3439 ,  A61B18/1445 ,  A61B18/1492 ,  A61B2017/00575 ,  A61B2017/00867 ,  A61B2017/306 ,  A61B2017/3445 ,  A61B2018/00214 ,  A61B2018/00261 ,  A61B2018/00285 ,  A61B2018/00291 ,  A61B2018/00351 ,  A61B2018/00619 ,  A61B2018/0063 ,  A61B2018/00702 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00898 ,  A61B2018/1472 ,  A61B2090/3614 ,  C08L2201/12

摘要： Methods and apparatus for treatment of patent foramen ovale (PFO) provide for applying energy to tissues adjacent the PFO with a catheter device to substantially close the PFO acutely. Apparatus generally includes a catheter device having at least one energy transmission member at or near its distal end configured to apply energy to PFO tissues to acutely, substantially close the PFO. Applied energy may be monoploar or bipolar radiofrequency energy or any other suitable energy, such as laser, microwave, ultrasound, resistive heating or the like. Some embodiments of a catheter device further include one or more tissue apposition members near the distal end for helping bring PFO tissues together, such as a PFO covering member, a vacuum applying member and/or the like. PFO closure via energy-based approaches of the invention may help prevent stroke, treat migraine headache, and possibly treat or prevent other medical conditions.

摘要翻译： 用于治疗卵圆孔卵泡（PFO）的方法和装置提供用导管装置向邻近PFO的组织施加能量，以基本上封闭PFO。 装置通常包括导管装置，其具有在其远端处或其近端处的至少一个能量传递构件，其被配置为向PFO组织施加能量以急剧，基本上关闭PFO。 应用能量可以是单极或双极射频能量或任何其它合适的能量，例如激光，微波，超声波，电阻加热等。 导管装置的一些实施例还包括靠近远端的一个或多个组织定位构件，用于帮助使PFO组织在一起，例如PFO覆盖构件，真空施加构件等。 通过基于本发明的基于能量的方法的PFO闭合可以有助于预防中风，治疗偏头痛，并且可能治疗或预防其它医疗状况。

公开(公告)号：US08133221B2

公开(公告)日：2012-03-13

申请号：US11771528

申请日：2007-06-29

申请人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson Gifford ,  Jose Alejandro

发明人： William Malecki ,  Dan Francis ,  Kenneth Horne ,  Mark E. Deem ,  Hanson Gifford ,  Jose Alejandro

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B2017/00575 ,  A61B2018/00214 ,  A61B2018/00291 ,  A61B2018/00351

摘要： Methods for treating anatomic tissue defects such as patent foramen ovale (PFO) generally involve positioning a distal end of an elongate catheter device at the site of the anatomic defect, exposing an expandable housing and energy transmission member out of the distal end of the catheter device, engaging the housing with tissues at the site of the anatomic defect, applying suction to the tissues via the housing to bring the tissues together; and applying energy to the tissues with the energy transmission member to substantially close the anatomic defect acutely. Apparatus generally include an elongate catheter body, a housing extending from a distal end of the catheter body for engaging tissues at the site of the anatomic defect, and an energy transmission member adjacent a distal end of the housing, the energy transmission member having at least one substantially planar surface.

摘要翻译： 用于治疗解剖组织缺陷如卵圆孔（PFO）的方法通常涉及将细长导管装置的远端定位在解剖缺损部位，将可扩张的壳体和能量传递构件暴露于导管装置的远端 将所述壳体与所述解剖缺陷部位的组织接合，通过所述壳体向所述组织施加吸力以将所述组织带在一起; 以及用能量传递构件向组织施加能量以急剧地基本上闭合解剖缺陷。 装置通常包括细长的导管主体，从导管主体的远端延伸的壳体，用于接合解剖缺陷部位的组织，以及邻近壳体的远端的能量传递构件，能量传递构件至少具有 一个基本平坦的表面。