专利检索 ap:("William N. HAINING" OR "Arlene H. SHARPE" OR "Jernej GODEC" OR "Dana-Farber Cancer Institute, Inc." OR "President AND Fellows of Harvard College") AND inv:"Jernej Godec" 第 1 页

1.

发明申请
Methods and Compositions for Perturbing Gene Expression in Hematopoietic Stem Cell Lineages In Vivo 审中-公开

公开(公告)号：US20170215392A1

公开(公告)日：2017-08-03

申请号：US15314251

申请日：2015-05-27

申请人： William N. HAINING , Arlene H. SHARPE , Jernej GODEC , Dana-Farber Cancer Institute, Inc. , President and Fellows of Harvard College

发明人： William N. Haining , Arlene H. Sharpe , Jernej Godec

IPC分类号： A01K67/027 , G01N33/50 , A61K49/00 , C12N5/0783 , C12N5/0781 , C12N15/86 , C12N15/11

CPC分类号： A01K67/0271 , A01K2207/12 , A01K2227/105 , A01K2267/025 , A61K35/28 , A61K49/0008 , C12N5/0635 , C12N5/0636 , C12N15/11 , C12N15/86 , C12N2310/11 , C12N2310/14 , C12N2310/141 , C12N2310/531 , C12N2740/15041 , C12N2740/15043 , C12N2840/002 , G01N33/505 , G01N33/5052 , G01N33/5088

摘要： The invention provides methods and compositions for perturbing gene expression in hematopoietic cell lineages in vivo.

2.

发明授权
Methods and compositions for perturbing gene expression in hematopoietic stem cell lineages in vivo 有权

公开(公告)号：US10653123B2

公开(公告)日：2020-05-19

申请号：US15314251

申请日：2015-05-27

申请人： Dana-Farber Cancer Institute, Inc. , President and Fellows of Harvard College

发明人： William N. Haining , Arlene H. Sharpe , Jernej Godec

IPC分类号： A01K67/027 , A61K35/28 , A61K49/00 , C12N5/0781 , C12N5/0783 , C12N15/11 , C12N15/86 , G01N33/50

摘要： The invention provides methods and compositions for perturbing gene expression in hematopoietic cell lineages in vivo.

3.

发明授权
Compositions and methods for identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators 有权

公开(公告)号：US10927410B2

公开(公告)日：2021-02-23

申请号：US15518860

申请日：2015-10-16

申请人： Dana-Farber Cancer Institute, Inc. , President and Fellows of Harvard College

发明人： William N. Haining , Arlene H. Sharpe , Jernej Godec

IPC分类号： C12N5/02 , C12Q1/6881 , G01N33/569 , C12Q1/6883

摘要： The present invention is based on the identification, of compositions and methods for the identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators.

4.

发明申请
COMPOSITIONS AND METHODS FOR IDENTIFICATION, ASSESSMENT, PREVENTION, AND TREATMENT OF T-CELL EXHAUSTION USING CD39 BIOMARKERS AND MODULATORS 审中-公开

公开(公告)号：US20170233808A1

公开(公告)日：2017-08-17

申请号：US15518860

申请日：2015-10-16

申请人： Dana-Farber Cancer Institute, Inc. , President and Fellows of Harvard College

发明人： William N. Haining , Arlene H. Sharpe , Jernej Godec

IPC分类号： C12Q1/68 , G01N33/569

CPC分类号： C12Q1/6881 , C12Q1/6883 , C12Q2600/106 , C12Q2600/158 , G01N33/56972 , G01N2333/70517 , G01N2333/70596 , G01N2800/52

摘要： The present invention is based on the identification, of compositions and methods for the identification, assessment, prevention, and treatment of T-cell exhaustion using CD39 biomarkers and modulators.