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公开(公告)号:US6103527A
公开(公告)日:2000-08-15
申请号:US19689
申请日:1998-02-06
IPC分类号: C12N15/09 , A61K38/00 , A61K38/17 , A61K38/19 , A61K39/00 , A61K39/395 , A61K48/00 , A61P7/02 , A61P7/06 , A61P9/00 , A61P25/00 , A61P29/00 , A61P31/00 , A61P35/02 , A61P37/00 , A61P37/08 , C07K14/52 , C07K14/705 , C12N5/10 , C12N15/00 , C12N15/11 , C12N15/12 , C12N15/85 , C12R1/91
CPC分类号: C07K14/70596 , A61K48/00
摘要: The promoter of the human endoglin gene, parts thereof, and compositions containing these are useful for high level control of gene expression, particularly in endothelial cells. The promoter, and promoter active portions of the promoter are shown to have unexpected activity and are particularly relevant for therapeutic use.
摘要翻译: 人内皮因素基因的启动子,其部分以及含有它们的组合物可用于高水平控制基因表达,特别是在内皮细胞中。 启动子的启动子和启动子活性部分显示具有意想不到的活性,并且对于治疗用途特别有用。