1-Propyl-triazolyl antimycotic compositions and methods of treating
mycoses
    1.
    发明授权
    1-Propyl-triazolyl antimycotic compositions and methods of treating mycoses 失效
    1-丙基 - 三唑基抗真菌组合物和治疗真菌病的方法

    公开(公告)号:US4079142A

    公开(公告)日:1978-03-14

    申请号:US638754

    申请日:1975-12-08

    IPC分类号: C07D249/08 A61K31/41

    CPC分类号: C07D249/08

    摘要: Pharmaceutical compositions are produced which comprise an antimycotically effective amount of a compound of the formula ##STR1## or a pharmaceutically acceptable non-toxic salt thereof wherein R.sup.1 is an unsubstituted or substituted aryl moiety,R.sup.2 is hydrogen, alkyl, alkenyl, cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted aralkyl, andR.sup.3 is hydrogen, alkyl or cycloalkyl,Provided that when R.sup.3 is hydrogen, R.sup.2 cannot be hydrogen, in combination with a pharmaceutically acceptable non-toxic inert diluent or carrier.

    摘要翻译: 制备药物组合物,其包含抗真菌有效量的下式化合物或其药学上可接受的无毒盐,其中R 1是未取代或取代的芳基部分,R 2是氢,烷基,烯基,环烷基,未取代的或未取代的 取代的芳基或未取代或取代的芳烷基,并且R 3是氢,烷基或环烷基,当R3是氢时,R2不能是氢,与药学上可接受的无毒惰性稀释剂或载体组合。

    1,2,4-Triazole antimycotic compositions and use thereof
    5.
    发明授权
    1,2,4-Triazole antimycotic compositions and use thereof 失效
    1,2,4-三唑抗真菌组合物及其用途

    公开(公告)号:US4002763A

    公开(公告)日:1977-01-11

    申请号:US532191

    申请日:1974-12-12

    IPC分类号: C07D249/08 A61K31/41

    摘要: Antimycotic compositions are produced which comprise an antimycotically effective amount of a 1,2,4-triazole of the formula: ##STR1## or a pharmaceutically acceptable non-toxic salt thereof wherein X.sup.1 is hydrogen or alkyl;X.sup.2 is hydrogen or alkyl;R.sup.1 is alkyl, unsubstituted or substituted aryl or unsubstituted or substituted aralkyl;R.sup.2 is hydrogen, alkyl or unsubstituted or substituted aryl;R.sup.3 is alkyl, cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted aralkyl; andY is a keto group of a functional derivative of a keto group, in combination with a pharmaceutically acceptable non-toxic, inert diluent or carrier.

    摘要翻译: 产生抗真菌组合物,其包含抗真菌有效量的下式的1,2,4-三唑或其药学上可接受的无毒盐,其中X 1是氢或烷基; X2是氢或烷基; R1是烷基,未取代或取代的芳基或未取代或取代的芳烷基; R2是氢,烷基或未取代或取代的芳基; R3是烷基,环烷基,未取代或取代的芳基或未取代或取代的芳烷基; 和Y是酮基的功能性衍生物的酮基,其与药学上可接受的无毒惰性稀释剂或载体的组合。

    1,2,4-Triazole antimycotic compositions and use thereof
    8.
    发明授权
    1,2,4-Triazole antimycotic compositions and use thereof 失效
    1,2,4-三唑抗真菌组合物及其用途

    公开(公告)号:US4036967A

    公开(公告)日:1977-07-19

    申请号:US645946

    申请日:1976-01-02

    IPC分类号: C07D249/08 A61K31/41

    摘要: Antimycotic compositions are produced which comprise an antimycotically effective amount of a 1,2,4-triazole of the formula: ##STR1## or a pharmaceutically acceptable non-toxic salt thereof wherein X.sup.1 is hydrogen or alkyl;X.sup.2 is hydrogen or alkyl;R.sup.1 is alkyl, unsubstituted or substituted aryl or unsubstituted or substituted aralkyl;R.sup.2 is hydrogen, alkyl or unsubstituted or substituted aryl;R.sup.3 is alkyl, cycloalkyl, unsubstituted or substituted aryl or unsubstituted or substituted aralkyl; andY is a keto group or a functional derivative of a keto group, in combination with a pharmaceutically acceptable non-toxic, inert diluent or carrier.

    摘要翻译: 产生抗真菌组合物,其包含抗真菌有效量的下式的1,2,4-三唑或其药学上可接受的无毒盐,其中X 1是氢或烷基; X2是氢或烷基; R1是烷基,未取代或取代的芳基或未取代或取代的芳烷基; R2是氢,烷基或未取代或取代的芳基; R3是烷基,环烷基,未取代或取代的芳基或未取代或取代的芳烷基; 和Y是酮基或酮基的官能衍生物,与药学上可接受的无毒惰性稀释剂或载体组合。