公开(公告)号：US06862533B2

公开(公告)日：2005-03-01

申请号：US09876142

申请日：2001-06-08

申请人： Wolfgang Strehlau ,  John Michael Newsam ,  Dirk Demuth ,  Wolfram Stichert ,  Armin Brenner ,  Stephan A. Schunk ,  Jens Klein

发明人： Wolfgang Strehlau ,  John Michael Newsam ,  Dirk Demuth ,  Wolfram Stichert ,  Armin Brenner ,  Stephan A. Schunk ,  Jens Klein

IPC分类号： B01J19/00 ,  C07B61/00 ,  C40B30/08 ,  C40B40/18 ,  G06F19/16 ,  G01N31/00

CPC分类号： B01J19/0046 ,  B01J2219/00689 ,  B01J2219/00695 ,  B01J2219/007 ,  B01J2219/00702 ,  B01J2219/0072 ,  B01J2219/00745 ,  B01J2219/00747 ,  B01J2219/00754 ,  C40B30/08 ,  C40B40/18 ,  G06F19/16

摘要： The invention relates to a method for the automated production and iterative automated optimization of a substance library and/or at least one reaction parameter relating to a performance characteristic comprising at least two substances comprising the steps of: a) defining at least one production parameter and at least one test parameter; b) automated preparation of a substance library by producing at least two substances on the basis of the at least one production parameter; c) automated testing of the at least two substances of the substance library with respect to at least one performance characteristic on the basis of the at least one test parameter; d) evaluating the test using electronic data analysis; e) varying the at least one production parameter and/or the at least one test parameter for optimizing the performance characteristics, and single or repeated repetition of steps b) to e) or c) to e); characterized in that the steps b) to e) are carried out in an integrated automated process.

摘要翻译： 本发明涉及用于物质文库的自动生产和迭代自动优化的方法和/或与包括至少两种物质的性能特征相关的至少一个反应参数的方法，包括以下步骤：a）定义至少一个生产参数和 至少一个测试参数; b）通过基于至少一个生产参数生产至少两种物质来自动制备物质文库; c）基于所述至少一个测试参数，相对于至少一个性能特征自动测试所述物质文库的至少两种物质; d）使用电子数据分析评估测试; e）改变所述至少一个生产参数和/或所述至少一个测试参数以优化所述性能特征，以及步骤b）至e）或c）至e）的单个或重复重复; 其特征在于步骤b）至e）以综合自动化过程进行。