公开(公告)号：US09034916B2

公开(公告)日：2015-05-19

申请号：US14009526

申请日：2011-11-28

申请人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Yu Jin Kim ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

发明人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Yu Jin Kim ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

IPC分类号： A01N43/02 ,  A61K31/335 ,  A01N43/08 ,  A61K31/34 ,  A01N37/00 ,  A61K31/21 ,  A01N31/14 ,  A61K31/075 ,  A01N31/00 ,  A61K31/045 ,  A61K31/357 ,  A61K36/83

CPC分类号： A61K31/357 ,  A61K36/83

摘要： The present invention relates to: a pharmaceutical composition or a Nurr1 activating composition for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the composition comprises an active ingredient in the form of genkwanin N or yuanhuacine, a Daphne genkwa extract comprising one or more of the above compounds, or a fraction thereof; or a functional food additive for preventing or alleviating a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the additive comprises genkwanin N or yuanhuacine, a Daphne genkwa extract comprising one or more of the above compounds, or a fraction thereof; and a method for the prevention or treatment of a neurodegenerative disease or a disease induced by impaired Nurr1 function, wherein the method comprises the step of administering the pharmaceutical composition.

摘要翻译： 本发明涉及：用于预防或治疗神经退行性疾病或由Nurr1功能受损引起的疾病的药物组合物或Nurr1活化组合物，其中所述组合物包含以genkwanin N或元花胺形式的活性成分，达芙妮 genkwa提取物包含一种或多种上述化合物或其一部分; 或用于预防或减轻神经退行性疾病或由Nurr1功能受损引起的疾病的功能性食品添加剂，其中所述添加剂包括genkwanin N或元华辛，包含一种或多种上述化合物的Daphne genkwa提取物或其一部分; 以及用于预防或治疗由Nurr1功能受损引起的神经变性疾病或疾病的方法，其中所述方法包括施用所述药物组合物的步骤。

公开(公告)号：US09114155B2

公开(公告)日：2015-08-25

申请号：US14009596

申请日：2012-04-06

申请人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

发明人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

IPC分类号： A61K36/73 ,  A61K36/738

CPC分类号： A61K36/73 ,  A61K36/738

摘要： The present invention relates to a pharmaceutical composition for preventing or treating Parkinson's disease, which comprises, as an active ingredient, a Rhodotypos scandens extract obtained by extracting the stem of Rhodotypos scandens with an organic solvent, and a food additive showing the effect of preventing or treating Parkinson's disease, the food additive comprising Rhodotypos scandens extract as an active ingredient. The Rhodotypos scandens extracts of the present invention may prevent or treat Parkinson's disease without producing any particular side effects, and therefore can be widely used for more safely treating Parkinson's disease.

摘要翻译： 本发明涉及一种用于预防或治疗帕金森病的药物组合物，其包含作为活性成分的通过用有机溶剂提取红景天甙茎的获得的红景霉素提取物，以及显示出预防或 治疗帕金森病，食品添加剂包含红景天提取物作为活性成分。 本发明的红景天提取物可以预防或治疗帕金森氏病，而不产生任何特定的副作用，因此可广泛用于更安全地治疗帕金森病。

公开(公告)号：US20140370132A1

公开(公告)日：2014-12-18

申请号：US14009596

申请日：2012-04-06

申请人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

发明人： Won Gon Kim ,  Baek Soo Han ,  Kyoung Shim Kim ,  Kwang Soo Kim ,  Young Mi Kang ,  Chun Hyung Kim ,  Mi Jin Sohn ,  Hoe Yune Jung

IPC分类号： A61K36/73

CPC分类号： A61K36/73 ,  A61K36/738

摘要： The present invention relates to a pharmaceutical composition for preventing or treating Parkinson's disease, which comprises, as an active ingredient, a Rhodotypos scandens extract obtained by extracting the stem of Rhodotypos scandens with an organic solvent, and a food additive showing the effect of preventing or treating Parkinson's disease, the food additive comprising Rhodotypos scandens extract as an active ingredient. The Rhodotypos scandens extracts of the present invention may prevent or treat Parkinson's disease without producing any particular side effects, and therefore can be widely used for more safely treating Parkinson's disease.

摘要翻译： 本发明涉及一种用于预防或治疗帕金森病的药物组合物，其包含作为活性成分的通过用有机溶剂提取红景天甙茎的获得的红景霉素提取物，以及显示出预防或 治疗帕金森病，食品添加剂包含红景天提取物作为活性成分。 本发明的红景天提取物可以预防或治疗帕金森氏病，而不产生任何特定的副作用，因此可广泛用于更安全地治疗帕金森病。