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1.发明申请Method For Producing An Acellular Dermal Matrix, And Acellular Dermal Matrix Produced By Same 有权生产无细胞真皮基质的方法，以及产生的无细胞真皮基质公开(公告)号：US20120329034A1
公开(公告)日：2012-12-27
申请号：US13580248
申请日：2010-06-11
申请人： Wook Chun , Weon Ik Choi , Joon Pio Hong , Hyun Seung Ryu
发明人： Wook Chun , Weon Ik Choi , Joon Pio Hong , Hyun Seung Ryu
IPC分类号： C12N5/071
CPC分类号： A61L27/362 , A61L27/3687 , A61L27/60 , A61L2430/40
摘要： The present invention relates to a method for producing an acellular dermal matrix, and to an acellular dermal matrix produced by same, and more particularly, to a method for producing an acellular dermal matrix, in which sucrose is added to base ingredients consisting of glycerol, propylene glycol, and a base solvent or solution so as to produce a cryoprotectant, the solution is injected into the skin below the epidermis and dermis from which cells have been removed, and freeze-drying is then performed.
摘要翻译： 本发明涉及一种生产无细胞真皮基质的方法，以及由其制备的无细胞真皮基质，更具体地说，涉及一种生产无细胞真皮基质的方法，其中将蔗糖加入到由甘油， 丙二醇和碱性溶剂或溶液中，以产生冷冻保护剂，将溶液注入表皮以外的皮肤以及从其中除去细胞的真皮，然后进行冷冻干燥。
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2.发明授权公开(公告)号：US09623149B2
公开(公告)日：2017-04-18
申请号：US13580248
申请日：2010-06-11
申请人： Wook Chun , Weon Ik Choi , Joon Pio Hong , Hyun Seung Ryu
发明人： Wook Chun , Weon Ik Choi , Joon Pio Hong , Hyun Seung Ryu
CPC分类号： A61L27/362 , A61L27/3687 , A61L27/60 , A61L2430/40
摘要： The present invention relates to a method for producing an acellular dermal matrix, and to an acellular dermal matrix produced by same, and more particularly, to a method for producing an acellular dermal matrix, in which sucrose is added to base ingredients consisting of glycerol, propylene glycol, and a base solvent or solution so as to produce a cryoprotectant, the solution is injected into the skin below the epidermis and dermis from which cells have been removed, and freeze-drying is then performed.
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公开(公告)号：US11013228B2
公开(公告)日：2021-05-25
申请号：US13386111
申请日：2010-06-11
申请人： Weon Ik Choi , Wook Chun , Jae Deuk Jung
发明人： Weon Ik Choi , Wook Chun , Jae Deuk Jung
摘要： The present invention relates to a method of processing allograft skin for transplantation and a cryopreserved allograft skin produced thereby. More specifically, the present invention relates to a method in which a cryoprotectant is prepared by adding sucrose to basic constituents comprising dimethyl sulfoxide, an animal cell culture medium and fetal bovine serum, and then the resulting solution is used to subject skin tissue for transplantation to a freezing process.
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4.发明申请Production Method For Cryopreserved Acellular Dermal Matrix, And Cryopreserved Acellular Dermal Matrix Produced Thereby 审中-公开冷冻保存的无细胞真皮基质和冷冻保存的无细胞真皮基质的生产方法公开(公告)号：US20120189707A1
公开(公告)日：2012-07-26
申请号：US13392596
申请日：2010-09-09
申请人： Wook Chun , Weon Ik Choi , Man Seong Park , Geun Hyung Kim , Jae Deuk Jung
发明人： Wook Chun , Weon Ik Choi , Man Seong Park , Geun Hyung Kim , Jae Deuk Jung
CPC分类号： A61L27/60 , A01N1/0221 , A61L27/362 , A61L27/3687 , A61L2430/40
摘要： The present invention relates to a production method for cryopreserved acellular dermal matrix and to cryopreserved acellular dermal matrix produced thereby, and more specifically it relates to a method in which a cryopreservation agent is made by adding sucrose to basic components consisting of glycerol and a basic solution and in which the resulting solution is used in the cryopreservation of skin tissue from which the cells in the epidermis and dermis have been removed, and relates to cryopreserved acellular dermal matrix produced thereby.
摘要翻译： 本发明涉及一种冷冻保存的无细胞真皮基质的制备方法和由此制备的冷冻保存的无细胞真皮基质，更具体地涉及一种方法，其中通过将蔗糖加入到由甘油和碱性溶液组成的碱性组分中来制备冷冻保存剂 并且其中所得溶液用于从其中去除表皮和真皮细胞的皮肤组织的冷冻保存，并涉及由此产生的冷冻保存的无细胞真皮基质。
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5.发明申请Method Of Processing Allograft Skin For Transplantation, And Cryopreserved Allograft Skin Produced Thereby 审中-公开处理同种异体移植皮肤的方法和由此产生的冷冻保存的同种异体移植皮肤公开(公告)号：US20120122071A1
公开(公告)日：2012-05-17
申请号：US13386111
申请日：2010-06-11
申请人： Weon Ik Choi , Wook Chun , Jae Deuk Jung
发明人： Weon Ik Choi , Wook Chun , Jae Deuk Jung
IPC分类号： A01N1/02
CPC分类号： A01N1/0221
摘要： The present invention relates to a method of processing allograft skin for transplantation and a cryopreserved allograft skin produced thereby. More specifically, the present invention relates to a method in which a cryoprotectant is prepared by adding sucrose to basic constituents comprising dimethyl sulfoxide, an animal cell culture medium and fetal bovine serum, and then the resulting solution is used to subject skin tissue for transplantation to a freezing process.
摘要翻译： 本发明涉及一种处理用于移植的同种异体移植皮肤的方法和由此产生的冷冻保存的同种异体移植皮肤。 更具体地说，本发明涉及通过向包含二甲基亚砜，动物细胞培养基和胎牛血清的碱性成分中加入蔗糖来制备冷冻保护剂的方法，然后将所得溶液用于皮肤组织移植 冻结过程。
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