专利检索 ap:("XBRANE BIOPHARMA AB" OR "CLONEOPT AB") AND inv:"Daniel DALEY" 第 1 页

1.

发明公开
SYNTHETICALLY EVOLVED DNA CONSTRUCTS FOR REGULATING SIGNAL PEPTIDE PERFORMANCE AS WELL AS VECTORS, HOST CELLS AND RECOMBINANT PROTEINS THEREOF 审中-公开

公开(公告)号：US20240301432A1

公开(公告)日：2024-09-12

申请号：US17797560

申请日：2021-02-05

申请人： XBRANE BIOPHARMA AB , CLONEOPT AB

发明人： Kiavash MIRZADEH , Daniel DALEY , Patrick SHILLING

IPC分类号： C12N15/62 , C12N15/67 , C12N15/70 , C12P21/02

CPC分类号： C12N15/625 , C12N15/67 , C12N15/70 , C12P21/02 , C07K2319/02

摘要： The present invention provides a simple and inexpensive system for regulating signal peptide performance by using a synthetically evolved nucleotide sequence. The invention further relates to an expression vector comprising the nucleotide sequence. Additionally, the present invention relates to host cell comprising the expression vector. Furthermore, the present invention relates to a recombinant protein expressed by the host cell as well as a method for expressing the recombinant protein.